Publications by authors named "Dan Weinfeld"

Article Synopsis
  • Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma often occur together and share similar pathological traits, but healthcare is typically divided by specialties, leading to a need for integrated treatment approaches.
  • A group of 16 experienced physicians in northern Europe discussed ways to improve global airways care through better screening, collaboration, and education among specialties, providing practical recommendations and identifying gaps in research.
  • The findings emphasize the importance of joint management to optimize care for adults with CRSwNP and asthma, suggesting that interdisciplinary clinics could enhance early recognition and treatment across related airway diseases.
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Article Synopsis
  • - The study investigated whether increasing the dose of intralymphatic immunotherapy (ILIT) for allergic rhinitis could improve safety and effectiveness after standard treatments, comparing two groups of patients with different vaccination backgrounds.
  • - Results showed that while higher doses were generally safe after traditional treatment, they didn't significantly improve symptoms or quality of life, and serious reactions occurred at lower doses in unvaccinated patients.
  • - The findings suggest that high-dose ILIT may benefit patients who still experience symptoms after standard therapy, but caution against exceeding certain dosages in previously unvaccinated individuals.
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Background: Allergen specific IgG4 levels have been monitored as a surrogate marker for the tolerance inducing effect of subcutaneous immunotherapy (SCIT) in many studies. Its accuracy at group level has been well established, but IgG4 has not yet found its place in the daily care of immunotherapy patients.

Methods: Intralymphatic immunotherapy (ILIT) is a novel route for allergy vaccination against pollen allergy, where an ultrasound-guided injection of 1000 SQ-U Alutard is given directly into a groin lymph node.

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Allergen-specific immunotherapy (AIT) is the only allergy treatment that confers long-term symptom amelioration for patients suffering from allergy. The most frequently used allergen application route is subcutaneous injection (SCIT), commonly taken as the gold standard, followed by sublingual (SLIT) or oral (OIT) application of allergen preparations. This is an up-to-date review of the clinical evidence for a novel route of allergen application, i.

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Background: A change in neural responsiveness may occur as the result of allergic inflammation in the lower airways as well as in the upper airways. In the lower airways, capsaicin cough sensitivity is known to reflect sensory neural reactivity.

Objective: The aim of this study was to establish whether allergic inflammation changes airway neural sensory reactivity during prolonged allergen exposure.

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