The genus Akodon is one of the most species-rich rodent lineages in South America. In Peru, this genus contains 14 species subdivided in two groups: aerosus and boliviensis. Akodon orophilus Osgood, 1913 (Rodentia: Cricetidae) is a member of the Akodon aerosus group that inhabits the northern Peruvian montane forest, but is poorly characterized and its distribution is vaguely known.
View Article and Find Full Text PDFRev Peru Med Exp Salud Publica
November 2013
Cancer can develop to the extent tumor cells grow, divide and grow into other body tissues. Integrins are a family of cell-surface heterodimeric receptors that play an important role in the development of tumor angiogenesis, growth and metastasis, thus being recognized as an attractive therapeutic target. Snake venom contains low-molecular weight peptides known as "disintegrins" that bind to integrins with high affinity, and prevent their action in cancer.
View Article and Find Full Text PDFRev Peru Med Exp Salud Publica
March 2012
Objectives: To develop an immunization protocol in order to produce avian IgY immunoglobulins against Bothrops atrox Peruvian snake venom and to evaluate its neutralizing capacity.
Materials And Methods: Six Hy Line Brown hens were immunized each two weeks using 500μg/doses of B. atrox venom in a period of two months.