Impact of the gut microbiota-Th17 cell axis on inflammatory depression.

Depression is a serious cognitive disorder that results in significant and pervasive deficits in social behavior. These deficits can be traced back to the intricate interplay between social, psychological, and biological factors. Inflammatory depression, a treatment-resistant or non-responsive subtype of depression, may be related to the interaction between the gut microbiota and interleukin-17-producing CD4 T cells (Th17 cells).

Bushen Huoxue acupuncture ameliorates Alzheimer's disease by upregulating MARCHF3 to induce NLRP3 ubiquitination and inhibit caspase-1-dependent pyroptosis.

Alzheimer's disease (AD) is a common neurodegenerative disorder that places a heavy burden on patients and society. Hippocampal neuronal loss is a hallmark of AD progression. Therefore, understanding the mechanism underlying hippocampal neuronal death would be of great importance for the diagnosis and treatment of AD.

Infantile bacterial meningitis combined with sepsis caused by : A case report.

Background: (SGSP) is a rare pathogen responsible for infant sepsis and meningitis and is potentially overlooked because it is not included in routine group B streptococcal screenings. Hence, we present a case of SGSP-induced infant meningitis and sepsis, accompanied by bronchopneumonia induced by multidrug-resistant (MRSA), providing insights into the identification, management, and prognosis of this bacterial infection.

Case Summary: A 45-day-old female infant presented with two episodes of high fever (maximum temperature: 39.

Unravelling the Effect of Crystal Facet of Derived-Copper Catalysts on the Electroreduction of Carbon Dioxide under Unified Mass Transport Condition.

Altering the physical structure and chemical property of copper, i.e., particle size, surface morphology, composition or crystal facet, has been demonstrated to be effective in steering the selectivity of products in electrochemical reduction of carbon dioxide.

Dynamic changes of the immune microenvironment in the development of gastric cancer caused by inflammation.

Precancerous lesions typically precede gastric cancer (GC), but the molecular mechanisms underlying the transition from these lesions to GC remain unclear. Therefore, it is urgent to understand this transition from precancerous lesions to GC, which is crucial for the early diagnosis and treatment of GC. In this study, we merged multiple single-cell RNA sequencing datasets to investigate the molecular changes in distinct cell types associated with the progression of GC.

ERP29 regulates the proliferation of endometrial carcinoma via M6A modification.

Aims: Endoplasmic reticulum protein 29 (ERP29) is crucial for endoplasmic reticulum stress (ERS). M6A plays an important role in the progression of endometrial cancer (EC). The study investigated the role of ERS-related gene (ERP29) and m6A in EC.

Enhancing pv. sensitivity in kiwifruit by repressing the NBS-LRR genes through miRNA-215-3p and miRNA-29-3p identification.

Kiwifruit bacterial canker, caused by pv. (PSA), poses a grave threat to the global kiwifruit industry. In this study, we examined the role of microRNAs (miRNAs) in kiwifruit's response to PSA.

Temporal variations in absorption and translocation of heavy metal(loid)s in pak choi (Brassica rapa L.) under open-field and greenhouse cultivation.

Elucidating the absorption and translocation of heavy metal(loid)s by common vegetables across different growth environments and stages is crucial for conducting accurate environmental risk assessments and for associated control. This study investigated temporal variations in the absorption and translocation capacities of pak choi (Brassica rapa L.) for As, Cd, Cr, Cu, Pb, and Zn in polluted soils during the plant growth cycle under greenhouse and open-field cultivation modes.

Boosting Interfacial Electron Transfer and CO Enrichment on ZIF-8/ZnTe for Selective Photoelectrochemical Reduction of CO to CO.

Artificial photosynthesis is an effective way of converting CO into fuel and high value-added chemicals. However, the sluggish interfacial electron transfer and adsorption of CO at the catalyst surface strongly hamper the activity and selectivity of CO reduction. Here, we report a photocathode attaching zeolitic imidazolate framework-8 (ZIF-8) onto a ZnTe surface to mimic an aquatic leaf featuring stoma and chlorophyll for efficient photoelectrochemical conversion of CO into CO.

Updates on Hydrogen Value Chain: A Strategic Roadmap.

A strategic roadmap for noncarbonized fuels is a global priority, and the reduction of carbon dioxide emissions is a key focus of the Paris Agreement to mitigate the effects of rising temperatures. In this context, hydrogen is a promising noncarbonized fuel, but the pace of its implementation will depend on the engineering advancements made at each step of its value chain. To accelerate its adoption, various applications of hydrogen across industries, transport, power, and building sectors have been identified, where it can be used as a feedstock, fuel, or energy carrier and storage.

EPAS1, a hypoxia- and ferroptosis-related gene, promotes malignant behaviour of cervical cancer by ceRNA and super-enhancer.

Hypoxia and Ferroptosis are associated with the malignant behaviour of cervical cancer. Endothelial PAS domain-containing protein 1 (EPAS1) contributes to the progression of cervical cancer. EPAS1 plays important roles in hypoxia and ferroptosis.

High carrier mobility along the [111] orientation in CuO photoelectrodes.

Solar fuels offer a promising approach to provide sustainable fuels by harnessing sunlight. Following a decade of advancement, CuO photocathodes are capable of delivering a performance comparable to that of photoelectrodes with established photovoltaic materials. However, considerable bulk charge carrier recombination that is poorly understood still limits further advances in performance.

Prevalence and Risk Factors of Poststroke Dysphagia: A Meta-Analysis.

Introduction: In patients with stroke, poststroke dysphagia (PSD) is a common complication that plays an important role in morbidity and mortality. The aim of this paper was to assess the prevalence and risk factors of PSD using a systemic review and meta-analysis.

Methods: PubMed, Embase, Cochrane Library, and Web of Science databases were systematically searched for potentially eligible studies published until September 2023.

Application of hydroxypropyl methylcellulose to improve the wettability of chitosan coating and its preservation performance on tangerine fruits.

Hydroxypropyl methylcellulose (HPMC) was employed as an intermediate layer to enhance interfacial interaction between chitosan (CS) coating and tangerine fruits, thereby improving the preservation effect. Owing to the low surface tension of tangerine fruit (26.04 mN/m), CS coating solutions showed poor wetting properties on fruit peels (contact angle > 100°).

Efficient CuO Photocathodes for Aqueous Photoelectrochemical CO Reduction to Formate and Syngas.

Photoelectrochemical carbon dioxide reduction (PEC-COR) represents a promising approach for producing renewable fuels and chemicals using solar energy. However, attaining even modest solar-to-fuel (STF) conversion efficiency often necessitates the use of costly semiconductors and noble-metal catalysts. Herein, we present a CuO/GaO/TiO photocathode modified with Sn/SnO catalysts through a simple photoelectrodeposition method.

Polylactic acid-based microcapsules for moisture-triggered release of chlorine dioxide and its application in cherry tomatoes preservation.

Polylactic acid (PLA)-based microcapsules, capable of releasing chlorine dioxide (ClO) upon exposure to moisture, have been developed for fruits and vegetables preservation. The microcapsules were prepared by emulsion solvent evaporation, utilizing PLA as the wall material, and NaClO as the core material. After optimization, NaClO microcapsules exhibited an encapsulation efficiency of 55.

From the West to the East: an evidence-based educational reform for modern medical students in traditional Chinese medicine learning.

Introduction: Generally, Traditional Chinese Medicine (TCM) courses are now given to modern medicine students without proper course scheduling, resulting in poor teaching results.

Methods: To analyze the main factors affecting TCM learning, we surveyed the medical students and TCM teachers from Xiangya School of Medicine of Central South University via online questionnaires. The questionnaire comprised two parts, the students' part included the basic information, the subjective cognition in TCM, the attitude toward TCM course arrangements, and the attitude toward curriculum content and the design of TCM.

Variations in Rhizospheric and Endophytic Root Fungal Communities of Scrophularia ningpoensis in Different Producing Areas.

Few studies have examined the association of factors associated with soil fertility and composition with the structure of microbial communities in the rhizosphere and endosphere. Hence, this study aimed to explore the effects of geographical differences on fungal communities in the roots of Scrophularia ningpoensis and the relationship between the fungal communities and secondary metabolic components in the host plant. We found that there was greater diversity in the fungal communities of the rhizosphere compartment than in endosphere communities.

Pyrimidinergic receptor P2Y6 expression is elevated in lung adenocarcinoma and is associated with poor prognosis.

Backgroud: Previous in vitro studies have indicated that pyrimidinergic receptor P2Y6 (P2RY6, P2Y6 receptor) may function as a cancer-promoting factor in lung adenocarcinoma (LUAD). However, the prognostic significance of P2RY6 expression in LUAD has not been investigated.

Objective: This study aimed to assess the impact of P2RY6 expression on the survival of patients with LUAD.

Photoelectrochemical CO Reduction at a Direct CuInGaS/Electrolyte Junction.

Photoelectrochemical (PEC) CO reduction has received considerable attention given the inherent sustainability and simplicity of directly converting solar energy into carbon-based chemical fuels. However, complex photocathode architectures with protecting layers and cocatalysts are typically needed for selective and stable operation. We report herein that bare CuInGaS photocathodes can drive the PEC CO reduction with a benchmarking 1 Sun photocurrent density of over 2 mA/cm (at -2 V vs Fc/Fc) and a product selectivity of up to 87% for CO (CO/all products) production while also displaying long-term stability for syngas production (over 44 h).

Electrochemical synthesis of propylene from carbon dioxide on copper nanocrystals.

The conversion of carbon dioxide to value-added products using renewable electricity would potentially help to address current climate concerns. The electrochemical reduction of carbon dioxide to propylene, a critical feedstock, requires multiple C-C coupling steps with the transfer of 18 electrons per propylene molecule, and hence is kinetically sluggish. Here we present the electrosynthesis of propylene from carbon dioxide on copper nanocrystals with a peak geometric current density of -5.

Exfoliated 2D Layered and Nonlayered Metal Phosphorous Trichalcogenides Nanosheets as Promising Electrocatalysts for CO Reduction.

Two-dimensional (2D) materials catalysts provide an atomic-scale view on a fascinating arena for understanding the mechanism of electrocatalytic carbon dioxide reduction (CO ECR). Here, we successfully exfoliated both layered and nonlayered ultra-thin metal phosphorous trichalcogenides (MPCh ) nanosheets via wet grinding exfoliation (WGE), and systematically investigated the mechanism of MPCh as catalysts for CO ECR. Unlike the layered CoPS and NiPS nanosheets, the active Sn atoms tend to be exposed on the surfaces of nonlayered SnPS nanosheets.