Publications by authors named "Dan Ratner"
Article Synopsis
- Research on Alzheimer's disease (AD) has struggled to find effective treatments, often due to a narrow focus on specific pathogenic mechanisms, but targeting multiple pathways could be more beneficial.
- The peptide GHK, particularly in its GHK-Cu form, is known for promoting healing, reducing inflammation, and improving cognitive function in aging mice.
- A study using 5xFAD mice showed that intranasal GHK-Cu treatment delayed cognitive decline, reduced amyloid plaques, and lowered inflammation, indicating its potential as a promising AD therapy that warrants further investigation.
Article Synopsis
- Brain aging leads to common cognitive impairments in older adults, with early cognitive decline being particularly prevalent and linked to increased dementia risk.
- Recent research indicates that GHK-Cu, a naturally occurring peptide, shows promise in treating age-related cognitive decline by potentially enhancing cognitive functions and reducing neuroinflammation.
- In studies with aged mice, those treated with intranasal GHK-Cu demonstrated improved memory and learning abilities, paving the way for further exploration of this treatment in future clinical trials.
A 32-year-old woman with locally invasive and metastatic endometrial cancer was admitted to the hospital for the treatment of crescendo pain. The effectiveness of her medical and psychosocial care was mitigated by four issues: (1) the intractable nature of her pain, (2) substance abuse, (3) mental illness, and (4) interorganizational conflict. This case report is both a chronicle and review of the literature of these multiple issues that converged together to adversely effect the patient's overall care.
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