Publications by authors named "Dan Makrinos"

Article Synopsis
  • mRNA-1647 is an experimental mRNA vaccine targeting cytomegalovirus (CMV) that stimulates immune responses by encoding specific viral proteins.
  • In a phase 1 trial, healthy adults who received three doses developed strong neutralizing antibodies and increased memory B cells, which persisted for months.
  • The vaccine effectively triggered robust T-cell responses, indicating its potential for further clinical development to combat CMV, a virus that poses risks, especially to vulnerable populations.
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