Publications by authors named "Dan Mai"

Significance: The conventional optical properties (OPs) reconstruction in spatial frequency domain (SFD) imaging, like the lookup table (LUT) method, causes OPs aliasing and yields only average OPs without depth resolution. Integrating SFD imaging with time-resolved (TR) measurements enhances space-TR information, enabling improved reconstruction of absorption () and reduced scattering () coefficients at various depths.

Aim: To achieve the stratified reconstruction of OPs and the separation between and , using deep learning workflow based on the temporal and spatial information provided by time-domain SFD imaging technique, while enhancing the reconstruction accuracy.

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We present a wide-field illumination time-domain (TD) diffusion optical tomography (DOT) for three-dimensional (3-D) reconstruction within a shallow region under the illuminated surface of the turbid medium. The methodological foundation is laid on the single-pixel spatial frequency domain (SFD) imaging that facilitates the adoption of the well-established time-correlated single-photon counting (TCSPC)-based TD detection and generalized pulse spectrum techniques (GPST)-based reconstruction. To ameliorate the defects of the conventional diffusion equation (DE) in the forward modeling of TD-SFD-DOT, mainly the low accuracy in the near-field region and in profiling early-photon migration, we propose a modified model employing the time-dependent δ-P approximation and verify its improved accuracy in comparison with both the Monte Carlo and DE-based ones.

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A single-pixel imaging technique applied to fluorescence spatial frequency domain imaging (f-SFDI) brings many positive benefits, but its low frame rate will also lead to severe quantitative degradation when dynamically imaging a vibrant target. This work presents a novel, to the best of our knowledge, single-pixel imaging approach that combines the extended Kalman filtering (EKF) and a cyclic one-pattern updating for an enhanced dynamic f-SFDI. The cyclic one-pattern updating scheme enables the dynamic imaging at a high frame rate, and on this basis, the imaging process of an intensity temporally varying target (assuming no structure motion in the scene) is dynamically modelled, and accordingly, the surface intensities and images at each sampling time point simultaneously estimated via the EKF.

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Introduction: Eating behaviors encompass disordered eating behaviors (e.g., overeating, binge eating, and associated symptoms of binge eating) and intuitive eating.

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We have proposed the profile-based intensity and frequency corrections for single-snapshot spatial frequency domain (SFD) imaging to mitigate surface profile effects on the measured intensity and spatial frequency in extracting the optical properties. In the scheme, the spatially modulated frequency of the projected sinusoidal pattern is adaptively adjusted according to the sample surface profile, reducing distortions of the modulation amplitude in the single-snapshot demodulation and errors in the optical property extraction. The profile effects on both the measured intensities of light incident onto and reflected from the sample are then compensated using Minnaert's correction to obtain the true diffuse reflectance of the sample.

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We present a spatial frequency domain (SFD) diffuse optical tomography for simultaneous acquisition of multi-wavelength tomographic images of turbid media. We propose a highly sensitive single-pixel SFD imaging system for simultaneously collecting multi-wavelength spatially modulated reflectance images, instead of using the expensive electron-multiplying charge-coupled device camera that requires switching between the multi-wavelength collections. The single-pixel SFD imaging system using three low-power light sources (455, 532 and 660 nm) that were intensity-modulated by square waves with three different frequencies for frequency encoding, and all the light sources were focused onto one digital micromirror device (DMD) for generating wide-field sinusoidal illumination patterns.

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In brain functional diffuse optical tomography, conventional indirect approaches first separately reconstruct the spatial changes in the absorption coefficients at every time point and then calculate the spatial excited levels in terms of hemodynamic models. Direct approaches combine the two steps necessary in the indirect approaches and obtain the spatial excited levels directly. Although reconstruction quality has been improved by the direct approaches to some extent, they still lack sharp edges and suffer from low spatial resolution because of the ill-posedness of the inverse problems.

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The aim of this study was to investigate the surgical methods and efficacies for cervicothoracolumbar spinal schwannoma (CSS). A total of 52 patients who had undergone treatment for schwannoma were retrospectively analyzed. Two methods were employed for the surgical resection of the thoracic and lumbar schwannomas: Type I (posterior midline approach semi-laminectomy with tumor resection and internal fixation with pedicle screws) was used in 24 cases, and type II (posterior midline approach laminectomy with tumor resection and internal fixation with pedicle screws) was used in 26 cases.

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Purpose: To evaluate the clinical effect of trabeculectomy combined amniotic membrane transplantation in refractory glaucoma.

Methods: Seventeen eyes of sixteen patients with uncontrolled glaucoma underwent trabeculectomy combined amniotic membrane transplantation. The mean follow-up was 11.

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