Validating the response surface method in entrepreneurship management research.

This study adapts an existing methodology in psychology to assess congruence relationships in entrepreneurship management. More specifically, it describes the application of a response surface method to examine the congruence effect of two predictor variables on an outcome variable. The study presents both visual and text presentations to serve as a guideline that can aid management researchers in adapting the method.

LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation.

Galectin-3 (Gal 3) is a glycan-binding protein that can be secreted by activated macrophages and mast cells at inflammation sites and plays an important role in inflammatory diseases caused by Bacteria and their products, such as lipopolysaccharides (LPS). Although it is well established that Gal 3 can interact with LPS, the pathophysiological importance of LPS/Gal 3 interactions is not fully understood. Data presented herein demonstrate for the first time that the interaction of Gal 3, either via its carbohydrate binding C-terminal domain or via its N-terminal part, with LPS from different bacterial strains, enhances the LPS-mediated neutrophil activation in vitro.