The adolescent origins of substance use disorders: a behavioral genetic perspective.

Over the past twenty years there has been an increasing recognition within the substance abuse research field that (SUDs) are usefully conceptualized within a developmental framework. That is, initiation of substance use in adolescence and escalation to substance abuse in early adulthood are strongly age-graded, with the relevant behavioral risk and protective factors manifesting early in development, often prior to substance use onset. In this chapter we review a program of research that seeks to provide a behavioral genetic perspective on the development of SUDs.