Publications by authors named "Dan Grinstein"

Tick-borne relapsing fever (TBRF) caused by is an endemic disease in Israel and highly prevalent in military personnel. Prevention among the Israel Defense Force soldiers is based on increased awareness mainly in hyperendemic areas and selective postexposure prophylaxis with doxycycline. In this study, we report the presence of a suspected outbreak of TBRF in four soldiers who spent 30 h inside a deserted bunker.

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Dogs have a key role in law enforcement and military work, and research with the goal of improving working dog performance is ongoing. While there have been intriguing studies from lab animal models showing a potential connection between the gut microbiome and behavior or mental health there is a dearth of studies investigating the microbiome-behavior relationship in working dogs. The overall objective of this study was to characterize the microbiota of working dogs and to determine if the composition of the microbiota is associated with behavioral and performance outcomes.

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Background: Post-Traumatic Stress Disorder (PTSD) symptoms include re-experiencing, avoidance, hyperarousal, and cognitive deficits, reflecting both emotional and cognitive dysregulation. In recent years, non-pharmacological approaches and specifically animal-assisted therapy have been shown to be beneficial for a variety of disorders such as Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and PTSD. However, little is mentioned in the literature about the reciprocal effects of the animal-human interaction.

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The ability to extract reliable segments from the sensory data-stream is necessary for learning and for creating a reliable representation of the environment. Here we focused on segmentation in visual learning associated with foraging. Fifty-one pigeons (Columba livia) were trained to recognize two food-predicting signals, one presented against fixed background elements and the other against varying backgrounds.

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Aggression in psychiatric wards is a continuing matter of concern for both patients and medical staff. Here we have tested the hypothesis that the frequency of such incidents can be reduced with a new strategy of using trained alert dogs that warn of impending violent outbursts. Dogs were positioned among patients in psychiatric wards.

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There is much current interest in materials that are made entirely or mostly of nitrogen atoms. Such materials, polynitrogens, may reveal new aspects of nitrogen chemistry, and are believed to provide a possible basis for novel energetic substances. An interesting family of such materials, in which the N group appears as a cation, was prepared by K.

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The first steps in the gas-phase decomposition mechanism of N3,N6-bis (1 H-tetrazol-5-yl)-1,2,4,5-tetrazine-3,6-diamine, BTATz, anions and the kinetic isotope effects in these processes were studied using combined multistage mass spectrometry (MS/MS) and computational techniques. Two major fragmentation processes, the exergonic loss of nitrogen molecules and the endergonic loss of hydrazoic acid, were identified. The observation of a primary isotope effect supported by calculations suggests that the loss of a nitrogen molecule from the tetrazole ring involves proton migration, either to or within the terazole ring, as a rate-determining step.

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The cyclopentazolate anion, N, has been researched extensively over the years and detected in the gas phase more than a decade ago, but was only recently measured in solution. The process whereby aryl pentazole reduction leads to the production of N is still not fully understood. Here, the production of N in solution was investigated using isotopic labeling techniques while implementing changes to the synthesis methodologies.

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Compelling evidence has been found for the formation and direct detection of the cyclopentazole anion (cyclo-N ) in solution. The anion was prepared from phenylpentazole in two steps: reduction by an alkali metal to form the phenylpentazole radical anion, followed by thermal dissociation to yield cyclo-N . The reaction solution was analyzed by HPLC coupled with negative mode mass spectrometry.

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The exposure to stress at different developmental time points has long been postulated to have a crucial impact on various brain structures involved in mental disorders. The long-term specific effects seem to emerge as a function of timing and duration of the exposure to stress, as well as the characteristics of the stressor. Previous studies have addressed this issue with an effort to describe a single "hyper-sensitive" time point, and have led to disagreement on a particular sensitive period for stress exposure.

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