Prevalence of dyslipidemia and its association with cardiometabolic factors and kidney function in the adult Romanian population: The PREDATORR study.

Unlabelled: The aims were to assess the prevalence and characteristics of dyslipidemia phenotypes in a Romanian population-based sample from the PREDATORR study.

Methods: PREDATORR was an epidemiological study with a cross-sectional, cluster random sampling design. Participants were classified into four dyslipidemia phenotypes based on the NCEP ATP III criteria: isolated hypertrigliceridemia, isolated hypoHDL-C, isolated hyperLDL-C and mixed dyslipidemia (≥2 standard lipid abnormalities).

Prevalence of diabetes mellitus and prediabetes in the adult Romanian population: PREDATORR study.

Background: The PREDATORR (PREvalence of DiAbeTes mellitus, prediabetes, overweight, Obesity, dyslipidemia, hyperuricemia and chronic kidney disease in Romania) study is the first national study analyzing the prevalence of diabetes mellitus (DM) and prediabetes, and their association with cardiometabolic, sociodemographic, and lifestyle risk factors in the Romanian population aged 20-79 years.

Methods: This was an epidemiological study with a stratified, cross-sectional, cluster random sampling design. Sociodemographic, lifestyle, and anamnestic data were collected through self- and interviewer-administered questionnaires, and biochemical assays and oral glucose tolerance tests were performed.

Microvesicles - potential biomarkers for the interrelations atherosclerosis/type 2 diabetes mellitus.

Microvesicles, also called microparticles or exosomes, are ultrastructural cellular components that have been widely researched in the past as well as present in order to establish their morphology, origin and role in physiological and pathological processes. Advanced techniques show that these microparticles have their clinical implications in the prevention and prediction in pathology and have potential in the discovery of novel therapeutic approaches to metabolic diseases such as diabetes, cardiovascular, autoimmune diseases and cancer.

Effects of lifestyle changes including specific dietary intervention and physical activity in the management of patients with chronic hepatitis C--a randomized trial.

Background: In patients with chronic hepatitis C (CHC), obesity is involved in the pathogenesis of insulin resistance, fatty liver disease and progression of fibrosis. The objective of this study was to compare a normoglucidic low-calorie diet (NGLCD) with a low-fat diet (LFD) among participants with CHC. Aimed to measure the impact of dietary changes in reduction of insulin resistance, obesity but also in steatosis and fibrosis.

The insulin polymorphism -23Hph increases the risk for type 1 diabetes mellitus in the Romanian population.

The insulin -23Hph and IGF2 Apa polymorphisms were genotyped in Romanian patients with T1DM (n = 204), T2DM (n = 215) or obesity (n = 200) and normoponderal healthy subjects (n = 750). The genotypes of both polymorphisms were distributed in concordance with Hardy-Weinberg equilibrium in all groups. The -23Hph AA genotype increased the risk for T1DM (OR: 3.

Improvements in life expectancy in type 1 diabetes patients in the last six decades.

Aims: To investigate the survival with diabetes in patients treated with insulin from diagnosis.

Subjects And Methods: We analyzed 845 subjects, 55.9% males, registered at "I.