The mental health and social emotional skills of students with different learning difficulties in China.

This study aimed to examine the mental health and social-emotional skills of individuals with mathematics difficulties (MD), reading difficulties (RD), and comorbid difficulties (MDRD) in China. Students with MD (n = 35), RD (n = 27), MDRD (n = 43), and typically-developing peers (TD, n = 167) completed the Children's Depression Inventory, the Children's Loneliness Questionnaire, the Social Anxiety Questionnaire, and the Survey on Social Emotional Skills (SSES). In regard to mental health, results showed that MDRD experienced significantly higher levels of loneliness compared to TD, while MD had significantly higher levels of depression than TD.

Multiple meningiomas of different variants in a single patient: illustrative cases.

Background: Meningiomas are the most common primary intracranial tumors, accounting for approximately one-third of all primary brain neoplasms, typically characterized by a single histological variant. Multiple meningiomas are a relatively rare occurrence in a single patient, particularly when exhibiting different histopathological variants.

Observations: The authors present the cases of three patients, each with two separate intracranial meningiomas of different variants.

The dynamic role of ferroptosis in cancer immunoediting: Implications for immunotherapy.

Currently, cancer immunotherapy strategies are primarily formulated based on the patient's present condition, representing a "static" treatment approach. However, cancer progression is inherently "dynamic," as the immune environment is not fixed but undergoes continuous changes. This dynamism is characterized by the ongoing interactions between tumor cells and immune cells, which ultimately lead to alterations in the tumor immune microenvironment.

Influence of static magnetic field pretreatment on the structure, physicochemical and functional properties of dietary fiber in corn sprouts.

Dietary fiber (DF) from corn sprouts, subjected to pretreatment with static magnetic field (SMF), was systematically investigated for its structural and functional characteristics using an enzymatic method. After SMF treatment, the surface of soluble DF showed higher pore density and pore structures, and insoluble DF showed more folds and a concave-convex surface profile. FT-IR and thermogravimetric analyses also showed that SMF pretreatment improved the functional group structure and thermal stability of DFs in corn sprouts.

Baoslingzhines Q-X: Structurally previously undescribed trace phenolic meroterpenoids from Ganoderma lucidum and their biological activities toward renal fibrosis and cytotoxicity.

Eight previously undescribed phenolic meroterpenoids baoslingzhines Q-X (1-8) including three enantiomeric (±)-baoslingzhines Q-S (1-3) harboring a 2-methylbenzofuran moiety, two trinormeroterpenoids baoslingzhines T and U (4 and 5) containing a 5-methylbenzyl motif as a connection point with another ring, an alkaloid baoslingzhine V (6) possessing 3-methylquinoline, were purified from Ganoderma lucidum. Their planar structures and the absolute configurations were elucidated based on spectroscopic methods and experimental electronic circular dichroism calculations. Compound 6 was capable of diminishing the expression of fibronectin and α-SMA, while compound 8 might dose-dependently attenuate fibronectin and collagen I expression.

Effects of Serum Insulin and Insulin-Like Growth Factor 1 Levels on the Association between Fetal Growth and Per- and Polyfluoroalkyl Substance Exposure Based on a Nested Case-Control Study.

Insulin and insulin-like growth factor 1 (IGF1) play key roles in fetal growth and development. However, their roles in the association between fetal growth and perfluoroalkyl and polyfluoroalkyl substance (PFAS) exposure remain unclear. In this study, the levels of 34 PFAS, IGF1, and insulin were measured in 258 paired mother-infant serum samples collected from a nested case-control study in Maoming city.

The clinical and neuroradiological features of hypertrophic olivary degeneration following brainstem stroke.

Objectives: Hypertrophic olivary degeneration (HOD), a rare type of trans-synaptic degeneration of the central nervous system (CNS) caused by disruption of the dentato-rubro-olivary pathway (DROP), is mainly described in the form of case reports. Our aim in this study is to summarize the clinical and imaging characteristics of patients with HOD following brainstem stroke.

Methods: A retrospective analysis was performed for all patients who were selected from electronic case databases between October 2019 and January 2024 in the Jiangxi Provincial People's Hospital and the Xinyu People's Hospital.

Innovative Nano Delivery Systems for Astaxanthin: Enhancing Stability, Bioavailability, and Targeted Therapeutic Applications.

Astaxanthin (AST), as a natural antioxidant, has broad application prospects in medicine and health products. However, its highly unsaturated structure and significant lipophilic characteristics limit its dispersibility and bioavailability, thereby restricting its application in food, medicines, and nutraceuticals. To overcome these limitations, researchers have proposed the use of nano delivery systems.

Standardization of Subcutaneous Injection of Prefilled Anticoagulants Through Lean Six Sigma Management: A Before-After Study.

Aim: The aim of this study was to investigate the impact of the Lean Six Sigma management approach on the standardization of nurses' prefilled anticoagulant subcutaneous injection practices, with a focus on improving anticoagulation outcomes, reducing patient complications, and enhancing overall patient satisfaction.

Background: The lack of standards for prefilled anticoagulant injection has resulted in a high complication rate, decreased patient satisfaction, and diminished service quality. This study investigated the impact of the Lean Six Sigma management approach on the standardization of nurses' prefilled anticoagulant subcutaneous injection practices.

Nourishment of Nerves and Innervation: A Novel Approach for the Treatment of Myocardial Infarction.

Background: Autonomic innervation of the heart plays a pivotal role not only in regulating the heart rate but also in modulating the cardiac cell microenvironment via cell-cell interactions and influencing the heart's repair capabilities. Currently, the primary clinical approach for treating myocardial infarction (MI) is percutaneous coronary intervention. However, the myocardial salvage rate remains low for patients with advanced disease.

Research Progress on Extracellular Matrix-Based Composite Materials in Antibacterial Field.

Due to their exceptional cell compatibility, biodegradability, and capacity to trigger tissue regeneration, extracellular matrix (ECM) materials have drawn considerable attention in tissue healing and regenerative medicine. Interestingly, these materials undergo continuous degradation and release antimicrobial peptides (AMPs) while simultaneously promoting tissue regeneration, thereby exerting a potent antibacterial effect. On this basis, a variety of basic properties of ECM materials, such as porous adsorption, hydrophilic adsorption, group crosslinking, and electrostatic crosslinking, can be used to facilitate the integration of ECM materials and antibacterial agents through physical and chemical approaches in order to enhance the antibacterial efficacy.

Environmental factors ultraviolet a and ozone exacerbate the repeated inhalation toxicity of 6PPD in mice via accelerating the aging reaction.

The burden of N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidized products on human health can no longer be ignored due to the detection types and concentrations in the environment continue to increase. Environmental ozone (O) and ultraviolet A (UVA) may induce ozonation and photoaging of 6PPD to produce toxic products. However, the impact of specific environmental conditions on the aging and toxic effects of 6PPD is unclear.

Effects of static magnetic field treatment on the digestive, structural and physicochemical characteristics of germinated corn starch.

Static magnetic field (SMF), an innovative and eco-friendly technology, has attracted widespread attention in the field of modified starch physicochemical properties. This study aimed to investigate the effects of SMF treatment on the structural and digestive properties of germinated corn (GC) starch. In vitro digestibility examination of GC starch revealed that SMF treatment (30 mT, 2 h) led to a 12.

Ameliorative effects of insoluble dietary fiber and its bound polyphenols from adzuki bean seed coat on acute murine colitis induced by DSS: The inflammatory response, intestinal barrier and gut microbiota.

The incidence of ulcerative colitis (UC) is closely associated with dietary fiber (DF) intake. This study aims to evaluate the ameliorative effects of insoluble dietary fiber from adzuki bean seed coat (AIDF) on dextran sulfate sodium (DSS)-induced UC in mice, both with and without bound polyphenols (BPs). We employed a model based on the "remove/backfill" of components.

Abnormalities along the cortico-medullary junction on brain MRI caused by 1,2-dichloroethane-induced toxic encephalopathy.

Background: 1,2-dichloroethane (DCE) induced toxic encephalopathy, a rare toxic disease of the central nervous system, is mainly reported in developing countries. Although clinicians have got some understanding about the clinical and neuroimaging features of 1,2-DCE-induced toxic encephalopathy, abnormality along the cortico-medullary junction on diffusion-weighted image (DWI) mimicking neuronal intranuclear inclusion disease (NIID) has not yet been described in this entity.

Case Presentation: We reported a patient with 1,2-DCE-induced toxic encephalopathy who was admitted to our department due to a 7-day history of nausea, vomiting, and cognitive decline.

Effects of Zeaxanthin on the Insulin Resistance and Gut Microbiota of High-Fat-Diet-Induced Obese Mice.

Obesity-induced insulin resistance (IR) can precipitate metabolic disorders such as diabetes. Zeaxanthin, a crucial member of the carotenoid family, has been found to mitigate the damage caused by obesity. However, reports on the effects of zeaxanthin on obesity-induced IR are lacking.

GLO1 regulates hepatocellular carcinoma proliferation and migration through the cell cycle pathway.

Background: Hepatocellular carcinoma (HCC) is a malignant tumor characterized by a high mortality rate. The occurrence and progression of HCC are linked to oxidative stress. Glyoxalase-1 (GLO1) plays an important role in regulating oxidative stress, yet the underlying mechanism remains unclear.

Improvement in Math Ability and Cognitive Processing in Children with Low Attention: An Intervention Based on PASS Theory.

This study investigates the effects of math training on math and cognitive performance among 8-9 year-old students with low attention. Fifty-six students with low attention were randomly assigned to a training group (n = 24) and a passive control group (n = 32). They completed math problem-solving, calculation fluency and PASS cognitive processing tests both before and after training.

The association between school bullying and executive functions in children and adolescents: A three-level meta-analysis.

Introduction: Even though existing amounts of results have shown that school bullying could be related to the main components of executive functions (EFs) (inhibitory control, working memory, and cognitive flexibility), research focused on this association yields inconsistent results.

Method: To address this research gap, the current study conducted a three-level meta-analysis approach and simultaneously considered the two perspectives of the bully and victim to clarify the relationship between school bullying experienced by children and EFs. It also explored the moderating variables that affect the relationship between school bullying and EFs.

Trends and frontiers in signal amplification for aptamer-based tumor detection: A bibliometric analysis.

Background: Malignant tumors are one of the leading causes of death worldwide, imposing a substantial economic and social burden. Early detection is the key to improving cure rates and reducing mortality rates, which requires the development of sensitive early detection technologies. Signal amplification techniques play a crucial role in aptamer-based early detection of tumors and are increasingly garnering attention from researchers.

Intrauterine exposure to long-chain perfluorocarboxylic acids (PFCAs) were associated with reduced primary bile acids in three-year-old children: Findings from a prospective birth cohort study.

Bile acids (BAs) play a crucial role in lipid metabolism of children. However, the association between per- and polyfluoroalkyl substance (PFAS) exposure and BAs in children is scarce. To address this need, we selected 252 children from the Maoming Birth Cohort and measured 32 PFAS, encompassing short- and long-chain perfluorocarboxylic acids (PFCAs) and perfluorosulfonic acids (PFSAs) in the cord blood.

SNORA28 Promotes Proliferation and Radioresistance in Colorectal Cancer Cells through the STAT3 Pathway by Increasing H3K9 Acetylation in the LIFR Promoter.

Radiotherapy is essential for treating colorectal cancer (CRC), especially in advanced rectal cancer. However, the low radiosensitivity of CRC cells greatly limits radiotherapy efficacy. Small nucleolar RNAs (snoRNAs) are a class of noncoding RNA that primarily direct post-transcriptional modifications of ribosomal RNAs (rRNAs), small nuclear RNAs (snRNAs), and other cellular RNAs.