Publications by authors named "Damodaran Premitha"

Background: The sexual interest of postmenopausal women is a crucial aspect of their overall well-being. Despite its importance, factors influencing postmenopausal sexual interest, particularly in Asian women, remain understudied and poorly understood.

Aims: To investigate the various factors influencing sexual interest in postmenopausal women in Malaysia.

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Article Synopsis
  • The Clinical Practice Guidelines aim to provide evidence-based recommendations for healthcare providers dealing with postmenopausal osteoporosis (OP) screening, diagnosis, and management.
  • A comprehensive literature review from 2014 onwards helped update the guidelines by formulating key clinical questions and evaluating relevant studies.
  • Recommended management includes assessing fracture risk, implementing non-pharmacological measures (like calcium intake and exercise), and choosing pharmacological treatments based on the patient's risk level, with regular assessments to adjust treatment as necessary.
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Addressing maternal malnutrition and its drivers is paramount in Southeast Asia. This article summarizes the key clinical learnings and evidence-based opinions from the experts to understand the need for vitamins and minerals supplementation, education, and self-care from preconception to the first 1000 days of life, which warranted further attention since COVID-19 pandemic. Evidence describing the importance of vitamins and minerals during preconception, pregnancy, and lactation stages was identified using literature databases.

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Iron deficiency anemia (IDA) is a major health burden among women in Asia. Key issues in IDA management in Asia are under-diagnosis and under-treatment. The lack of Asia-specific guidelines, and suboptimal utilization of treatment compounds the management of IDA.

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Article Synopsis
  • This Clinical Guidance focuses on helping practitioners assess and manage glucocorticoid-induced osteoporosis (GIO) by utilizing evidence-based recommendations.
  • A systematic literature review was conducted to update treatment guidelines from 2012, emphasizing early intervention for patients starting glucocorticoids, especially within the first 3-6 months when fracture risk rises.
  • Bisphosphonates are recommended as the primary treatment for GIO, particularly in post-menopausal women and older men, while younger individuals should only receive them if they have existing fractures or are at very high risk.
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Article Synopsis
  • The Clinical Guidance aims to assist healthcare practitioners in effectively assessing, diagnosing, and managing osteoporosis (OP) based on the best available evidence.
  • A comprehensive literature review, updating information from 2012, focused on identifying effective diagnostic and treatment strategies for both postmenopausal and male OP, highlighting the importance of using fracture risk assessment tools alongside bone density measurements.
  • Key recommendations include maintaining adequate calcium and vitamin D intake while emphasizing that pharmacological therapies, particularly anti-resorptives, are essential for confirmed OP, requiring regular assessment and adjustment of treatment plans for patients.
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Aim: This Clinical Guidance is aimed to help practitioners assess, diagnose and manage their patients with osteoporosis (OP), using the best available evidence.

Methods: A literature search using PubMed (MEDLINE) and The Cochrane Library identified all relevant articles on OP and its assessment, diagnosis and treatment, from 2005, to update from the previous edition published in 2006. The studies were assessed and the level of evidence assigned; for each statement, studies with the highest level of evidence were used to frame the recommendation.

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