Publications by authors named "Damilare O Lanipekun"
The straw-coloured fruit bats (Eidolon helvum) are the most widely distributed megachiropteran species in Africa. Studies have shown that they migrate, and are likely exposed to environmental pollutants across population. This study was designed to investigate genotoxicity via the bone marrow micronucleus assay and haematological alterations of Eidolon helvum in the tropics.
View Article and Find Full Text PDFObjectives: Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals. This work sought to study the role of gallic acid (GA), a known antioxidant, on the BPA-induced testicular oxidative stress in adult male Wistar rats using serum hormone analysis, histopathology, and biochemical assays.
Methods: Adult male rats were divided into four groups (n=10) including control (0.
Article Synopsis
- * Pregnant Wistar rats were divided into groups, some receiving BPA alone at varying doses and others receiving BPA with melatonin to assess its protective effects.
- * Results showed BPA exposure led to reduced body weight, hormonal imbalances, oxidative stress in the testis, and damage to reproductive tissues, while MLT co-treatment appeared to mitigate these adverse effects.
Article Synopsis
- * Male rats were divided into four groups: a control group, a group receiving MLT only, a group exposed to BPA, and a group exposed to both BPA and MLT.
- * Results showed that BPA led to significant increases in hormonal levels and various signs of toxicity in the adrenal glands, but the combined treatment with MLT helped reduce these harmful effects, indicating MLT's potential antioxidant benefits.
Article Synopsis
- Bisphenol A (BPA) is identified as an endocrine disrupting chemical that negatively affects the reproductive organs, while melatonin (ML) serves as a protective antioxidant against these effects.
- In a study involving adult male Wistar rats divided into four groups, those treated with BPA exhibited increased prostatic index and altered hormone levels, while concurrent administration of ML helped improve these adverse conditions.
- The study concludes that low doses of melatonin can mitigate the harmful effects of BPA on prostate health, as shown by improved hormonal balance and reduced structural damage in the prostate gland of rats.