Importance of measurements at or after the J-point for evaluation of ST-segment deviation and resolution during treatment for acute myocardial infarction.

Background: Determination of ST-segment deviation (STdev) and its resolution (STR) by reperfusion strategies have become important tools in the assessment of patients with acute myocardial infarction (AMI). STdev has been measured at different time-points, i.e.

ST-deviation reconstruction in missing leads on the 12-lead ECG: applicability in studies on ST-segment resolution during thrombolysis.

Quantitative analysis of ST-segment deviations (STdev) and their resolution by treatment (STR; calculated from a combined sum of STdev in multiple leads) are used in trials on reperfusion for myocardial infarction (MI). Unreadable or unavailable electrocardiogram (ECG) leads are a common reason for exclusion, decreasing the statistical power of the trials. We developed mathematical formulas for reconstruction of immeasurable STdev based on STdev from other available leads on the 12-lead ECG.