A novel clinical test for assessing patellar cartilage changes and its correlation with magnetic resonance imaging and arthroscopy.

Controversy still exists regarding the best clinical assessment test for chondromalacia patellae (CMP). Our study aims to evaluate the specificity and sensitivity of a novel clinical test for CMP, the "Patella Slide Test" (PST) against the findings of magnetic resonance imaging (MRI) and arthroscopy. We included 221 consecutive patients planned for elective knee arthroscopic surgery.

Effects of Myofascial Trigger Point Release on Power and Force Production in the Lower Limb Kinetic Chain.

Devereux, F, O'Rourke, B, Byrne, PJ, Byrne, D, and Kinsella, S. Effects of myofascial trigger point release on power and force production in the lower limb kinetic chain. J Strength Cond Res 33(9): 2453-2463, 2019-The purpose of this study was to first investigate the effects of treating latent myofascial trigger points (MTrPs) in the lower limb kinetic chain with respect to performance during sporting actions, as opposed to the traditional goal of pain management with active MTrPs.

Scoliosis and the Social Media: Facebook as a Means of Information Exchange.

Background Context: Over the last decade, the emergence of social networking websites such as Facebook have revolutionized information dissemination and broadened opportunities to engage in discussions. In particular, having been widely adopted in the younger generation, the use of this medium has become more prevalent in health disorders such as scoliosis in the adolescent population. However, the quality of information on Facebook is unregulated and variable, which may mislead patients in their decision making.

Interday Reliability of the Reactive Strength Index and Optimal Drop Height.

Byrne, DJ, Browne, DT, Byrne, PJ, and Richardson, N. Interday reliability of the reactive strength index and optimal drop height. J Strength Cond Res 31(3): 721-726, 2017-The purpose of this study was to investigate the interday reliability of the reactive strength index (RSI) and optimal drop height (ODH) identification from multiple drop heights.

The Oswestry Spinal Risk Index (OSRI): an external validation study.

Purpose: The Oswestry Spinal Risk Index (OSRI) was recently reported as an adjunct in the management of metastatic spinal disease. Based on the tumour type and a general condition score, survivorship is predicted. We aimed to externally validate this new score.

Clinico-pathological analysis of renal cell carcinoma demonstrates decreasing tumour grade over a 17-year period.

Introduction: Renal cell carcinoma (RCC) represents about 3% of adult malignancies in Ireland. Worldwide there is a reported increasing incidence and recent studies report a stage migration towards smaller tumours. We assess the clinico-pathological features and survival of patients with RCC in a surgically treated cohort.

Cauda equina syndrome: assessing the readability and quality of patient information on the Internet.

Study Design: A readability and quality control Internet-based study using recognized quality scoring systems.

Objective: To assess the readability and quality of Internet information relating to cauda equina syndrome accessed through common search engines.

Summary Of Background Data: Access to health-related Internet information has increased dramatically during the past decade.

Assessment of the quality and content of information on anterior cruciate ligament reconstruction on the internet.

The Internet has become a major source of health information for the public. However, there are concerns regarding the quality, accuracy, and currency of medical information available online. We assessed the quality of information about anterior cruciate ligament (ACL) reconstruction on the first 60 websites returned by the 4 most popular search engines.

Internet use by parents of children attending a dedicated scoliosis outpatient clinic.

Purpose: No information exists on the level of internet use among parents of pediatric patients with scoliosis. The internet may represent a medium through which to provide information to augment the outpatient consultation. The aim of this research was to establish the prevalence of internet use amongst a cohort of parents attending a pediatric scoliosis outpatient clinic.

Scoliosis-specific information on the internet: has the "information highway" led to better information provision?

Study Design: A quality-control Internet-based study using recognized quality scoring systems.

Objective: To evaluate the quality of information available on the Internet.

Summary Of Background Data: The quality of information available is of poor quality and unreliable, and this study was to determine if it has improved in line with the exponential increase in Internet-based information since the last time it was reviewed in 2005.

Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β.

Background: Matrix metalloproteinases are catabolic enzymes that play a key role in the articular cartilage degeneration evident in degenerative and inflammatory conditions of articular cartilage. The aim of this study is to assess the ability of pravastatin to modify matrix metalloproteinase (MMP) messenger RNA (mRNA) expression and enzyme activity in a culture of normal human chondrocytes stimulated by interleukin-1β.

Materials And Methods: Normal human chondrocytes were stimulated with interleukin (IL)-1β for 6 h to induce MMP expression, simulating a catabolic state, and then treated with pravastatin (1, 5 and 10 μM) for a further 18 h before cell lysates and supernatants were harvested.

Analgesic control and functional outcome after knee arthroscopy: results of a randomized double-blinded trial comparing a hyaluronic acid supplement with bupivacaine.

Objective: Hyaluronic acid (HA) is a naturally occurring substance within normal synovial joints. Although its efficacy in treating osteoarthritis has been evaluated, it has not been established whether it is of benefit after routine arthroscopic procedures. We hypothesized that immediate supplementation with HA after completion of arthroscopy would result in improved short-term analgesic and functional outcomes after knee arthroscopy.

The 25 most cited articles in arthroscopic orthopaedic surgery.

Purpose: The purpose of this study was to use Web of Knowledge to determine which published arthroscopic surgery-related articles have been cited most frequently by other authors by ranking the 25 most cited articles. We furthermore wished to determine whether there is any difference between a categorical "journal-by-journal" analysis and an "all-database" analysis in arthroscopic surgery and whether such a search methodology would alter the results of previously published lists of "citation classics" in the field. We analyzed the characteristics of these articles to determine what qualities make an article important to this subspecialty of orthopaedic surgery.

Can a periarticular levobupivacaine injection reduce postoperative opiate consumption during primary hip arthroplasty?

Background: Several reports have confirmed the ability of intraoperative periarticular injections to control pain after THA. However, these studies used differing combinations of analgesic agents and the contribution of each, including the local anesthetic agent, is uncertain. Understanding the independent effects of the various agents could assist in improved pain management after surgery.

Diagnostic accuracy of magnetic resonance imaging and magnetic resonance arthrography of the hip is dependent on specialist training of the radiologist.

Objective: Significant differences between magnetic resonance imaging reports and intraoperative findings at the time of hip arthroscopy were documented in our practice. We sought to examine the accuracy of radiological reporting of hip pathology based on the training level of the reporting radiologist.

Materials And Methods: A retrospective review of hip arthroscopies carried out between July 2008 and June 2009 identified 61 cases where original MRI scans had been reported by general community radiologists.

Analgesic control after hip arthroscopy: a randomised, double-blinded trial comparing portal with intra-articular infiltration of bupivacaine.

The optimum anaesthetic and analgesic management following hip arthroscopy is yet to be determined. There is, in addition, some concern over the use of intraarticular local anaesthetic. We compared the analgesic efficacy of intra-articular infiltration compared with portal infiltration of bupivacaine following hip arthroscopy.

Review article: Osteochondral reconstruction and grafting.

Osteochondral defects are a challenging problem. Osteochondral reconstruction and grafting techniques potentially benefit both young athletes and elderly osteoarthritis patients. Research on the treatment of osteochondral defects has been carried out, particularly on surgical options, but none shows lasting benefit.

Simulation of fracture healing in the tibia: mechanoregulation of cell activity using a lattice modeling approach.

In this study, a three-dimensional (3D) computational simulation of bone regeneration was performed in a human tibia under realistic muscle loading. The simulation was achieved using a discrete lattice modeling approach combined with a mechanoregulation algorithm to describe the cellular processes involved in the healing process-namely proliferation, migration, apoptosis, and differentiation of cells. The main phases of fracture healing were predicted by the simulation, including the bone resorption phase, and there was a qualitative agreement between the temporal changes in interfragmentary strain and bending stiffness by comparison to experimental data and clinical results.

Human chondrocyte viability after treatment with local anesthetic and/or magnesium: results from an in vitro study.

Purpose: We aimed to assess the effect on chondrocyte viability of adding magnesium to a variety of commonly available local anesthetic agents.

Methods: Human chondrocytes were grown under standard culture conditions. Cells were exposed to a local anesthetic agent with the addition of magnesium (10%, 20%, or 50%).

Post-operative opiate requirements after hip arthroscopy.

Purpose: Although hip arthroscopy continues to evolve in its use and its popularity grows, little attention has been paid to the anaesthetic and analgesic management of patients undergoing this procedure. We aimed to report on our initial experience of the anaesthetic and analgesic requirements of a consecutive series of patients undergoing hip arthroscopy.

Methods: We reviewed the surgical and anaesthetic records of the initial, consecutive 85 patients undergoing hip arthroscopy for any reason at our hospital.

Simulation of tissue differentiation in a scaffold as a function of porosity, Young's modulus and dissolution rate: application of mechanobiological models in tissue engineering.

Numerous experimental studies have attempted to determine the optimal properties for a scaffold for use in bone tissue engineering but, as yet, no computational or theoretical approach has been developed that suggests how best to combine the various design parameters, e.g. scaffold porosity, Young's modulus, and dissolution rate.

Predicting revision risk for aseptic loosening of femoral components in total hip arthroplasty in individual patients--a finite element study.

Advances in surgical procedure, prosthesis design, and biomaterials performance have considerably increased the longevity of total joint replacements. Preoperative planning is another step in joint replacement that may have the potential to improve clinical outcome for the individual patient, but has remained relatively consistent for a long time. One means of advancing this aspect of joint replacement surgery may be to include predictive computer simulation into the planning process.