Publications by authors named "Damian Garcia-Escudero"
Objectives: The objective of this study is to compare the early oncological outcomes of delayed (>90 days) versus scheduled (≤90 days) radical prostatectomy (RP).
Patients And Methods: Patients with prostate cancer due to undergo surgery between March 2020 and June 2020 who were enrolled in the COVIDSurg-Cancer international, observational study were prospectively followed up for 1 year. Time to surgery was defined as the difference between the operation date and the multi-disciplinary team decision to offer surgery.
Objective: The objective of this study was to report the 12-month oncological outcomes for patients with non-muscle-invasive bladder cancer (NMIBC) within the prospective, international COVIDSurg Cancer study.
Patients And Methods: Eligible patients were aged ≥18 years and scheduled for elective surgical management of NMIBC with curative intent (transurethral resection of bladder tumour [TURBT] or bladder biopsy) from 21 January to 14 April 2020. The primary outcome was disease recurrence within 12 months of previous elective TURBT/bladder biopsy.
Medium-term safety outcomes in patients undergoing tension free vaginal tape obturator for stress urinary incontinence in Murcia, Spain. Historical cohort.
Rev Colomb Obstet Ginecol
March 2021
Objective: Describe the medium-term safety of the tension free vaginal tape obturator (TVT-O) procedure in terms of complications, cure and changes in quality of life (QoL) after the surgery.
Materials And Methods: Descriptive historical cohort that included women over 18 years of age who underwent TVT-O due to objectively proven stress urinary incontinence, urethral hypermobility or mixed urinary incontinence in which the stress component predominated, confirmed on urodynamic testing between July 2013-April 2017, in a reference hospital located in the city of Murcia Spain. Women with previous anti-incontinence surgery, concomitant vaginal surgery and planning pregnancy were excluded.
Article Synopsis
- The study investigates the link between anogenital distance (AGD) and the risk of prostate cancer (CaP), aiming to expand on previous research about AGD as an indicator of prenatal androgen levels.
- A case-control study involved 260 men, where AGD measurements were taken, and the relationship between AGD and CaP was analyzed using various statistical methods.
- Results indicated that AGD could be a helpful clinical marker for diagnosing CaP, particularly in certain patient subgroups, despite its moderate sensitivity and specificity.
Article Synopsis
- The study looked at the connection between how far certain body parts are from each other (anogenital distance) and the risk of prostate cancer in men.
- Researchers measured this distance in 260 men, some with prostate cancer and some without, to see if it made a difference.
- They found that men with shorter anogenital distances were more likely to have prostate cancer compared to those with longer distances.
Article Synopsis
- - The study evaluated the connection between anogenital distance (AGD), a marker of prenatal androgen exposure, and the severity and prognosis of prostate cancer in 119 patients.
- - Researchers measured two types of AGD and conducted logistic regression analysis to determine their association with prostate cancer outcomes, focusing on biochemical recurrence and surgical specimen margins.
- - Results indicate that longer AGD, linked to higher prenatal androgen exposure, correlates with worse prognosis in prostate cancer cases.
Background: Anogenital distance (AGD), the distance from the centre of the anus to the genitals, is a sexually dimorphic phenotype in mammals. Experimental studies have shown that AGD is a biomarker of prenatal androgen exposure during the masculinisation period of development. The aim of this study is to assess the relationship between anogenital distance (AGD), as an indirect marker of prenatal hormonal environment, and prostate cancer (PCa) severity.
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