Baicalein, a natural flavonoid in gastrointestinal cancers treatment: recent trends and future perspectives.

Gastrointestinal cancer is a malignant condition of the gastrointestinal tract (GI) which affect multi-organs of digestive system, such as esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum, and anus. Gastrointestinal cancer is a 5th most common malignant cancer and 4th major cause in cancer-related mortality rate. Various significant facilities are available that have reduced the radio-resistance, chemo-resistance, and their adverse side effects.

Flavonoid-Mediated Suppression of Tumor Angiogenesis: Roles of Ang-Tie/PI3K/AKT.

Angiogenesis is a process involved in the formation of new blood capillaries from pre-existing ones. It is regulated by several anti-angiogenic molecules involved in tumor growth and metastasis. The endothelial angiopoietin Ang-Tie/PI3K/AKT growth receptor pathway is necessary for healthy vascular development.

Vaccine-based therapeutic interventions in lung cancer management: A recent perspective.

The incidence of lung cancer continues to grow globally, contributing to an ever-increasing load on healthcare systems. Emerging evidence has indicated lowered efficacy of conventional treatment strategies, such as chemotherapy, surgical interventions and radiotherapy, prompting the need for exploring alternative interventions. A growing focus on immunotherapy and the development of personalized medicine has paved the way for vaccine-based delivery in lung cancer.

Structural, luminescent and in vitro studies of europium-doped soda lime phosphate glasses.

In this article, we have reported the effect of varying concentration of europium (Eu) in (50 - x)% P O -25% Na O-24% CaO-% Eu O , where x = 1, 3, 5. The glass samples were synthesised via conventional melt-quench method. The impact of europium ion (Eu ) on the structural, optical and luminescent properties of phosphate soda lime glasses has been studied using X-ray diffraction (XRD), Fourier-transformed infrared (FTIR) spectroscopy, ultraviolet-visible spectroscopy, scanning electron microscopy coupled with energy-dispersive spectroscopy and photoluminescent techniques.

In-vitro bioactivity of silicate-phosphate glasses using agriculture biomass silica.

In the present work, silica extracted from the agricultural waste material; rice husk (RH) was utilized for the synthesis of biocompatible glass of general composition SiO-PO-CaO-MgO-MoO. In the synthesized glasses PO (5%) and CaO (25%) was kept constant whereas MgO and MoO was varied from 10% to 20% and 0% to 5% respectively. The structural, morphological, elemental and functional properties of silica as well as the derived glasses were analyzed by X-Ray Diffraction (XRD), Field Emission Scanning Electron Microscopy (FE-SEM), Energy Dispersive X-ray spectroscopy (EDX) and Fourier Transform Infrared (FTIR) spectroscopy techniques.