Publications by Dalya Saidi

Publications by authors named "Dalya Saidi"

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Formulation optimization of lyophilized aptamer-gold nanoparticles: Maintained colloidal stability and cellular uptake.

Dalya Saidi Marya Obeidat Shrouq Alsotari Abed-Alqader Ibrahim Rula Al-Buqain

Heliyon

May 2024

Anti-nucleolin (NCL) aptamer AS1411 is the first anticancer aptamer tested in clinical trials. Gold nanoparticles (AuNP) have been widely exploited for various biomedical applications due to their unique functional properties. In this study, we evaluated the colloidal stability and targeting capacity of AS1411-funtionalized AuNP (AuNP/NCL-Apt) against MCF-7 breast cancer cell line before and after lyophilization.

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