Intradermal Injection of Hybrid Complexes of High- and Low-Molecular-Weight Hyaluronan: Where Do We Stand and Where Are We Headed in Regenerative Medicine?

Hyaluronic acid (HA) is a remarkably multifaceted biomacromolecule, playing a role in regulating myriad biological processes such as wound healing, tissue regeneration, anti-inflammation, and immunomodulation. Crosslinked high- and low-molecular-weight hyaluronic acid hydrogels achieve higher molar concentrations, display slower degradation, and allow optimal tissue product diffusion, while harnessing the synergistic contribution of different-molecular-weight hyaluronans. A recent innovation in the world of hyaluronic acid synthesis is represented by NAHYCO Hybrid Technology, a thermal process leading to hybrid cooperative hyaluronic acid complexes (HCC).

The treatment of hyaluronic acid aesthetic interventional induced visual loss (AIIVL): A consensus on practical guidance.

Background: Visual loss (blindness) caused by injection of soft tissue fillers is a rare but devastating issue to both patient and practitioner. There is a lack of any structured protocol in the management of this problem AIMS: To produce a pathway for the management of hyaluronic acid aesthetic interventional induced visual loss that was based on the current available literature and guidelines. evidence proposed guidance for the practical management of this problem.

Cannula Versus Sharp Needle for Placement of Soft Tissue Fillers: An Observational Cadaver Study.

Background: Soft-tissue fillers have become important products for facial rejuvenation. Deep fat compartments and facial bones lose volume during the natural aging process. For the most natural-looking results, deep volumetric injections at strategic sites are therefore preferred.

Time and motion in cosmetic surgery.

Time and motion studies have been used to analyze performance and improve outcomes. This prospective study evaluated a typical operating day at a surgical facility in the United Kingdom by recording admitting time into the hospital, entrance and exit times from theatre, and length of surgical time. The same surgical team performed 10 breast augmentations in less than 10 hr, with a mean preparation time of 9 min 20 s and a mean surgical time (from incision to closure) of 32 min.

Lubricant and razor debridement in partial thickness burn.

By aiming to relieve pain from removing blisters in partial thickness burn, we tested whether the application of a sterile lubricant (KY-Jelly) on blisters and the use of a sterile razor to remove their roof can reduce algesia in humans, compared to a conventional method. A prospective randomized controlled designed study was performed on 20 patients. A visual pain scale was used by patients to evaluate pain experienced.