Publications by authors named "Dalton Haslam"
Article Synopsis
- SLC37A4 is a gene that codes for a protein essential for transporting glucose-6-phosphate into the endoplasmic reticulum, which is important for glucose metabolism, especially during times of glucose scarcity.
- Mutations in SLC37A4 lead to glycogen storage disorder 1b, which causes liver and kidney issues, along with a lack of certain white blood cells (neutropenia).
- Research on seven individuals with a specific mutation in SLC37A4 revealed liver dysfunction and abnormal serum glycans, and CRISPR technology was used to create liver cells mimicking the mutation's effects, connecting it to abnormal glycosylation and changes in cell structure.
Secretion of platelet granule constituents is closely associated with the phosphorylation of a cytosol polypeptide of Mr = 47,000 that we have called P47 (Haslam, R. J., Lynham, J.
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