Publications by authors named "Dall'Asta A"

Background: Occiput-posterior (OP) position is associated with labor arrest, need of operative delivery and failed instrumental vaginal delivery with resulting adverse peripartum outcomes. Vacuum extraction (VE) is the most commonly performed type of instrumental delivery worldwide. This study aimed to investigate the outcome of VE in fetuses with sonographically confirmed OP position prior to the procedure.

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Objective: The aim of this systematic review is to summarize the current evidence on preventive interventions and bundles, including combinations of multiple techniques, aimed at reducing vaginal delivery-related perineal injury.

Methods: A systematic research of literature was independently conducted on different databases (PubMed, MEDLINE, EMBASE) by the authors, using a combination of the identified keywords and index terms as per current PRISMA guidelines. The research was restricted to papers published in English starting by 2000.

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Objective: To compare the sonographic measurement of the umbilical cord between women with or without repetitive decelerations during the first stage of labor.

Study Design: Prospective study including a non-consecutive cohort of women at term gestation carrying a normal sized fetus at term in cephalic presentation. The cross-sectional area of the umbilical cord, of its vessels and the amount of the Wharton's jelly were assessed at 2D ultrasound upon labor admission.

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Novel Insights Continuous intrapartum fetal heart rate assessment by fetal scalp electrode may record arrythmias like recurrent atrial ectopic beats and depict an increased fetal heart rate variability mimicking a ZigZag pattern. Introduction Fetal scalp electrode (FSE) is considered the gold standard for the intrapartum monitoring of the fetal heart rate (FHR) being associated with the lowest rate of signal loss and artifacts including the recording of the maternal heart rate. FSE acquires a fetal electrocardiogram and evaluates the time intervals between successive R waves.

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Article Synopsis
  • * Research indicates that intrapartum US significantly improves predictions of labor outcomes, especially for women experiencing slow progression, and is more reliable than manual exams before instrumental deliveries.
  • * Guidelines are increasingly recommending the use of intrapartum US to verify fetal position, aiding in interventions like manual rotation of the fetal position and assisted breech delivery, ultimately enhancing safety in obstetric care.
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Introduction: Speckle tracking echocardiography is a non-Doppler modality allowing the semiautomated evaluation of the fetal cardiac function by tracking the speckles of the endocardial borders. Little evidence is available on the evaluation and comparison of different software for the functional assessment of the fetal heart by means of speckle tracking echocardiography. The aim of this study was to evaluate the reproducibility and agreement of two different proprietary speckle tracking software for the prenatal semiautomated assessment of the fetal cardiac function.

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Objectives: To develop a deep learning (DL)-model using convolutional neural networks (CNN) to automatically identify the fetal head position at transperineal ultrasound in the second stage of labor.

Material And Methods: Prospective, multicenter study including singleton, term, cephalic pregnancies in the second stage of labor. We assessed the fetal head position using transabdominal ultrasound and subsequently, obtained an image of the fetal head on the axial plane using transperineal ultrasound and labeled it according to the transabdominal ultrasound findings.

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Relative uteroplacental insufficiency of labor (RUPI-L) is a clinical condition that refers to alterations in the fetal oxygen "demand-supply" equation caused by the onset of regular uterine activity. The term RUPI-L indicates a condition of "relative" uteroplacental insufficiency which is relative to a specific stressful circumstance, such as the onset of regular uterine activity. RUPI-L may be more prevalent in fetuses in which the ratio between the fetal oxygen supply and demand is already slightly reduced, such as in cases of subclinical placental insufficiency, post-term pregnancies, gestational diabetes, and other similar conditions.

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Article Synopsis
  • In fetuses with open spina bifida at 11 to 13 weeks of gestation, the study found the size of the lateral ventricles was smaller than in normal fetuses, which contrasts the expected increase in size later in pregnancy.
  • The study aimed to compare various measurements of the lateral ventricles between fetuses with open spina bifida and a control group of normal fetuses, using detailed ultrasound data.
  • Results showed that fetuses with open spina bifida had a higher choroid plexus-to-lateral ventricle area ratio compared to controls (0.49 vs. 0.72), indicating a reduced amount of fluid in the ventricular system.
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Objectives: To describe the sonographic features of the caudothalamic groove in the third trimester of pregnancy in a group of structurally normal fetuses and to report a small series of cases with abnormal appearance of the caudothalamic groove at antenatal cranial ultrasound.

Methods: This was an observational study conducted at two fetal medicine referral units in Italy. A non-consecutive cohort of pregnant women with a singleton non-anomalous pregnancy were recruited prospectively and underwent three-dimensional (3D) ultrasound assessment of the fetal brain at 28-32 weeks' gestation.

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Article Synopsis
  • The study explores a new methodology for 3D ultrasound imaging of fetal faces, aimed at improving the diagnosis of genetic conditions during pregnancy.
  • Researchers analyzed 135 ultrasound volumes from fetuses aged 24-34 weeks, using a semi-automatic process to create 3D surface models that reflect normal growth patterns.
  • The findings indicate that as gestation advances, certain facial features change, and while growth-restricted fetuses have smaller faces, their shape remains consistent; this model could aid in identifying congenital anomalies linked to facial characteristics.
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Background: The evidence-based management of human labor includes the antepartum identification of patients at risk for intrapartum hypoxia. However, available evidence has shown that most of the hypoxic-related complications occur among pregnancies classified at low-risk for intrapartum hypoxia, thus suggesting that the current strategy to identify the pregnancies at risk for intrapartum fetal hypoxia has limited accuracy.

Objective: To evaluate the role of the combined assessment of the cerebroplacental ratio (CPR) and uterine arteries (UtA) Doppler in the prediction of obstetric intervention (OI) for suspected intrapartum fetal compromise (IFC) within a cohort of low-risk singleton term pregnancies in early labor.

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Objective: to investigate the correlation between the intrapartum CardioTocoGraphic (CTG) findings "suggestive of fetal inflammation" ("SOFI") and the interleukin (IL)-6 level in the umbilical arterial blood.

Study Design: prospective cohort study conducted at a tertiary maternity unit and including 447 neonates born at term.

Methods: IL-6 levels were systematically measured at birth from a sample of blood taken from the umbilical artery.

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Background: Agenesis of the corpus callosum is associated with several malformations of cortical development. Recently, features of focal cortical dysgyria have been described in fetuses with agenesis of the corpus callosum.

Objective: This study aimed to describe the "cortical invagination sign," a specific sonographic feature of focal cortical dysgyria, which is consistently seen at midtrimester axial brain ultrasound in fetuses with complete agenesis of the corpus callosum.

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Bone health starts with maternal health and nutrition, which influences bone mass and density already in utero. The mechanisms underlying the effect of the intrauterine environment on bone health are partly unknown but certainly include the 'foetal programming' of oxidative stress and endocrine systems, which influence later skeletal growth and development. With this narrative review, we describe the current evidence for identifying patients with risk factors for developing osteopenia, today's management of these populations, and screening and prevention programs based on gestational age, weight, and morbidity.

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Objectives: To evaluate the relationship between the attitude of the fetal head quantified by means of the chin-to-chest angle (CCA) in fetuses in occiput posterior (OP) position at the beginning of the second stage of labor, and persistent OP position at birth.

Methods: This was a single-center, prospective observational study conducted at the University Hospital of Parma, Parma, Italy. We included singleton pregnancies at term with fetuses in the OP position at the beginning of the second stage of labor.

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