Publications by authors named "Daljeet Bansal"

Novel products applying artificial intelligence (AI)-based methods to digital pathology images are touted to have many uses and benefits. However, publicly available information for products can be variable, with few sources of independent evidence. This review aimed to identify public evidence for AI-based products for digital pathology.

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Whole slide imaging (WSI) of pathology glass slides using high-resolution scanners has enabled the large-scale application of artificial intelligence (AI) in pathology, to support the detection and diagnosis of disease, potentially increasing efficiency and accuracy in tissue diagnosis. Despite the promise of AI, it has limitations. 'Brittleness' or sensitivity to variation in inputs necessitates that large amounts of data are used for training.

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Background: It has been argued that ethics review committees-e.g., Research Ethics Committees, Institutional Review Boards, etc.

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Digital pathology - the digitalisation of clinical histopathology services through the scanning and storage of pathology slides - has opened up new possibilities for health care in recent years, particularly in the opportunities it brings for artificial intelligence (AI)-driven research. Recognising, however, that there is little scholarly debate on the ethics of digital pathology when used for AI research, this paper summarises what it sees as four key ethical issues to consider when deploying AI infrastructures in pathology, namely, privacy, choice, equity, and trust. The themes are inspired from the authors' experience grappling with the challenge of deploying an ethical digital pathology infrastructure to support AI research as part of the National Pathology Imaging Cooperative (NPIC), a collaborative of universities, hospital trusts, and industry partners largely located across the North of England.

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Article Synopsis
  • The study investigates how the antagonist Decorin affects scar formation and wound healing in injured spinal cords of rats, focusing on acute and chronic dorsal funicular lesions (DFL).
  • Decorin treatment significantly reduced various injury parameters, including wound cavity size and fibrotic tissue markers, more effectively in acute injuries compared to chronic ones.
  • The findings suggest Decorin's primary role in acute injuries is to limit scar formation and inflammation by targeting TGF-β1/2, while in chronic injuries, it enhances the tissue remodeling process through the modulation of certain proteins involved in healing.
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