Rising Resistance In Uropathogens With An Indication Of Nitrofurantoin Mic Creep.

Background: The irrational use of antibiotics has led to the emergence of multi drug resistant pathogens. The phenomenon of MIC creeps occurs when organisms start showing raised MIC but within susceptible range giving an indication of the prevalence of rise in resistant pathogens in an area.

Methods: A cross sectional study in a large tertiary care hospital in North India to observe the susceptibility pattern among uropathogens and the possibility of MIC creeps.

Prevalence and antibiogram of non-fermenting Gram-negative bacilli in blood stream infections: Study in a tertiary care centre, Western Uttar Pradesh, India.

Non-fermenting Gram-negative bacilli (NFGNB) are emerging as important cause of blood stream infections. We aimed to determine the prevalence and antibiotic susceptibility pattern of NFGNB isolated from blood of patients with sepsis. We found, in 176 patients, the most common to be (74) and (39) followed by (16), (6), (5) and (1).

Geographical distribution of primary & secondary dengue cases in India - 2017: A cross-sectional multicentric study.

Background & Objectives: Dengue virus infection is endemic in India with all the four serotypes of dengue virus in circulation. This study was aimed to determine the geographic distribution of the primary and secondary dengue cases in India.

Methods: A multicentre cross-sectional study was conducted at Department of Health Research / Indian Council of Medical Research (DHR)/(ICMR) viral research and diagnostic laboratories (VRDLs) and selected ICMR institutes located in India.

Does circumcision alter the periurethral uropathogenic bacterial flora.

Background: The aim of this study was to assess the pattern of periurethral bacterial flora in uncircumcised boys and to evaluate the effect of circumcision on alteration of periurethral uropathogenic bacterial flora.

Materials And Methods: Pattern of periurethral bacterial flora before and after circumcision was studied prospectively in 124 boys. The results were analysed to compare change in bacterial colonisation before and after circumcision.

Novel route of infection in experimental model of hydatid disease.

Viable protoscolices of Echinococcus granulosus injected into Swiss-albino mice by two different routes, viz. intraperitoneal and subcutaneous and in two different concentrations of 2000 and 1000 scolices, to observe the development of cysts have shown that subcutaneous route of infecting a mouse model is superior because of its low infecting dose and longer survival period of mouse. This finding should be helpful in experiments to observe the effect of drugs for the treatment of hydatidosis, in vivo, without the need of killing the mouse.

Pulmonary pseudallescheriasis in a patient with healed tuberculosis.

Pulmonary pseudallescheriasis in an immunocompetent patient without a pre-existing cavity or cyst is a rare phenomenon. We report a case of invasive pulmonary pseudallescheriasis in a lobectomised patient treated for tuberculosis. Filamentous fungi with pyriform conidia were seen in the bronchoalveolar lavage fluid .

Methicillin-resistant Staphylococcus aureus: need for constant surveillance,stringent control and vigorous treatment measures.

Staphylococcus aureus has shown a disconcerting propensity to develop resistance to antimicrobial agents and an increasing proportion of these have become resistant to methicillin as well. Regular surveillance should be carried out in every hospital and stringent infection control measures and vigorous treatment should be employed to prevent the nosocomial spread of MRSA. A total of 1056 MRSA were isolated from various specimens received in bacteriology division of SKIMS Srinagar out of which 46.