The Impact of Thrombolytic Therapy on Anxiety, Depression and Quality of Life of Patients with Acute Ischemic Stroke.

Background: It is well established that thrombolytic therapy improves the functional recovery by reducing disability measured as National Institutes of Health Stroke Scale (NIHSS) and Rankin score in patients with ischemic stroke. However, the role of alteplase treatment on anxiety and depression in those patients is less clear. Therefore, the aim of this study was to determine whether patients treated with thrombolytic therapy had a better quality of life, less anxiety and depression compared to patients who were not treated with thrombolysis.