Polygonal boundary gaps in multiple diffusion source precipitation systems in gel media.

We investigate multiple reaction-diffusion processes that engender the formation of distinct precipitation zones. In this paper, we carry out various original precipitation reactions in a gel medium, wherein the interdiffusion of the co-precipitates occurs from various sources arranged in a symmetric framework in 2D Petri dishes. The distinct precipitation zones are separated by clear polygonal boundaries, in congruence with the spatial distribution of the diffusion holes hosting the outer electrolyte.

Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.

Despite the urgency for prevention and treatment of lung adenocarcinoma (LUAD), we still do not know drivers in pathogenesis of the disease. Earlier work revealed that mice with knockout of the G-protein coupled receptor Gprc5a develop late onset lung tumors including LUADs. Here, we sought to further probe the impact of Gprc5a expression on LUAD pathogenesis.