[Hepatitis B and pregnancy].

Background: Chronic Hepatitis B infection can lead to liver cirrhosis and hepatocellular carcinoma. In women, these viral infections can be responsible for transmission to the husband and to the child during delivery.

Aim: The purpose of this review is to analyze from the literature the mechanism of mother-to-child transmission and the consequences.

[Helicobacter pylori and gastric adenocarcinoma].

Background: Accumulating evidence for considering HP as a causal factor for gastric cancer comes from recent epidemiologic studies, the advent of an animal model of gastric cancer and from new insights in to the biological mechanisms for gastric carcinogenesis.

Aim: The purpose of this review is to analyze recent data from the literature on this relationship and try to define what kinds of preventive measures could be proposed

Methods: We conducted a review of the literature through the interrogation of the MEDLINE database using a query documentary by combining the Boolean (AND) keywords (MeSH) as follows: Helicobacter pylori, stomach neoplasms.

Results: HP infection, host genetic background, food regimen are known to be involved in this cancer.

[Crohn's disease: influence of age at diagnosis on clinical type of disease].

Unlabelled: The aim of the study was to examine the influence of age at diagnosis of Crohn's disease on disease site and course in Tunisian patients.

Methods: All hospital patients for Crohn's disease between 1993 and 2002 were included. They were segregated by age at diagnosis as follows: younger than 20 years, 20-39 years, and 40 years or older.

[Role of mitochondrial dysfunction in non-alcoholic steatohepatitis].

The non alcoholic steatohepatitis is a more and more frequent disease. Great progress in the physiopathologic mechanisms has been recently observed. The mitochondrial dysfunction seems to be the main mechanism implied in the necroticoinflammatory genesis of the non alcoholic steatohepatitis lesions.

[Predictive factors of recurrent hemorrhage in duodenal ulcer: report of 208 cases].

The aim of this study was to evaluate clinical, biological and endoscopic predictive factors of recurrent bleeding. Two hundred and eight patients (169 males/39 females) with a bleeding from duodenal ulcers, confirmed by an endoscopy, were included in a retrospective study performed over 3 years. Forrest classification was used to describe endoscopic stigmata of bleeding.

[Psychological disorder associated to inflammatory bowel disease].

The symptomatology of patients with ulcerative colitis or Crohn's disease is not only characterised by bowel related symptoms. There is indeed psychological and psychiatric comorbidity. Depression and anxiety seem to be more common.

[Management of ascitis in patients with cirrhosis].

Ascites is the most common complications of patients with cirrhosis. The treatment of ascites has been based on the ascitic volume. MODERATE ASCITIS: an oral diuretic and a low-salt diet are indicated.

[Predictive factors of recurrence after surgery in severe attacks of hemorrhagic ulcerative proctocolitis].

Aim: The purpose of our study was to determine clinical, biological or endoscopic factors that predict surgery after a glucocortico steroid treatment failure in severe attacks of ulcerative colitis.

Methods: Sixty one patients were analyzed. A therapeutic response for glucocorticosteroid was defined as the absence of resort to surgery within the first 30 days after hospitalization.

[Stromal tumors of the digestive tract: three small bowel localisation].

Background: Stromal tumors of the digestive tract are undifferenciated connective tissue tumors, identified as stemming of "pace-maker" cells of Cajal related to the immunohistochimical characterization of the phenotype.

Aim: Report three new cases

Case Report: We report three observations of the small bowel stromal tumors reveal by anemia in one case and mass formation in two cases. The aim of this study was to discuss the anatomo-clinical, prognosis and management of these tumors.

[Predictive factors of intestinal stenosis in Crohn's disease].

Unlabelled: The aim of our study was to determine demographic, clinical, biological or endoscopic factors that predict intestinal stenosis in Crohn's disease.

Patients And Methods: One hundred and twenty one patients were retrospectively analyzed during 10 years. The diagnosis of stenosis were determined by morphologic and endoscopic exams independently of appearance of symptoms.

[Epidemiologic profile of gastric carcinoma: study of 140 cases].

The authors make a retrospective study of a series of 140 patients aged 59 years in average, followed up from 1995 to 2002 for adenocarcinoma of the stomach. Surgical resection was performed in 79 percent of the patients with total gastrectomy in 15.4%, partial gastrectomy in 50.

[Renal amyloidosis complicating Crohn's disease: report of two cases and review of literature].

Secondary amyloidosis is caused by the extracellular store of the fragment AA of the circulatory protein in serum amyloid-A. It can complicate diseases such as family mediterranean fever, rheumatoid arthritis or Crohn's disease. Renal amyloidosis is a rare but serious complication of Crohn's disease.

[Importance of vaccination chronic hepatitis B].

Weak therapeutic responses and weak immune cytotoxic CD8 and CD4 response in chronic hepatitis B emphasize the necessity to find new therapeutic strategies especially as specific immunotherapy. Vaccination, whose principle was to widen immune repertoire, was used as a curative treatment of chronic hepatitis B. It would be the therapeutic procedure with the lowest cost and the potentially greatest benefit.

[Predictive factors of recurrence in Crohn's disease].

Background And Aims: The aim of this study is to determine the factors associated with high risk of recurrence of Crohn disease.

Patients And Methods: During 12 years period from January 1987 till December 1999, 98 patients treated for Crohn's disease were included in this study. The risk of recurrence was studied using the Kaplan-Meier method.

[Octreotide in the treatment of acute gastrointestinal hemorrhage caused by ruptured esophageal varices].

Aims: To asses the value of octreotide in the control of acute bleeding esophageal varices in a retrospective study.

Methodology: Fourty two patients admitted for esophageal variceal bleeding confirmed at endoscopy were recruited. An initial 50 micrograms bolus of octreotide followed by a two day continuous infusion of 25 micrograms/h were evaluated for the control of bleeding.

[Non alcoholic steatohepatitis: an emergent and potentially serious pathology].

Nonalcoholic steatohepatitis is an acquired liver disease, usually metabolic characterised by histologic lesions with steatosis, intralobular necrosis and inflammatory infiltrates. Liver biopsy findings are identical to those seen in alcoholic hepatitis. Nonalcoholic steatohepatitis is increasingly reported in industrial countries because of an increase of the prevalence of obesity and diabetes which are the most common risk factors of this disease.

[Biological markers of hepatocellular carcinoma].

Hepatocellular carcinoma is a rapidly fatal tumor. The only hope for a cure lies in early diagnosis. It follows that an effective screening strategy should be used in high-risk populations.

[Modalities and interest in followup of colorectal cancers after curative surgery].

Recurrence is found in 24 to 50% in patients undergoing surgery for colorectal cancer. The main purpose of follow-up is the screening of local or metastatic recurrence. Actually, the follow-up can not be justified only if there is a real advantage for the patient.

[Gastrointestinal stromal tumors. Current data].

GIST anatomical concept, recently elucidate, they are characterized by the expression of the protooncogene C Kit The diagnosis is relatively easy but prognosis evaluation is not usually possible. The treatment is based on the surgical resection. The rewardable clinical response of tumors that express C-Kit to treatment with the tyrosine kinase inhibitor STI 571 is a triumph of molecular pharmacology.

[Nephrogenic ascites. A case report].

Nephrogenic ascites is a clinical diagnosis defined as a refractory ascites in patients with end-stage renal disease. The exact cause of ascites formation is unknown. Patients frequently present with moderate to massive ascites and cachexia.