Publications by authors named "Dale Hawkins"
Multi-omics (genomics, transcriptomics, epigenomics, proteomics, metabolomics, etc.) research approaches are vital for understanding the hierarchical complexity of human biology and have proven to be extremely valuable in cancer research and precision medicine. Emerging scientific advances in recent years have made high-throughput genome-wide sequencing a central focus in molecular research by allowing for the collective analysis of various kinds of molecular biological data from different types of specimens in a single tissue or even at the level of a single cell.
View Article and Find Full Text PDFThis study describes the development of a resource module that is part of a learning platform named 'NIGMS Sandbox for Cloud-based Learning' https://github.com/NIGMS/NIGMS-Sandbox. The overall genesis of the Sandbox is described in the editorial NIGMS Sandbox at the beginning of this Supplement.
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- ATAC-seq is a technique used to study chromatin accessibility, which helps researchers understand gene regulation at both the cell population and single-cell levels.
- Comprehensive analysis of ATAC-seq data requires navigating a sequence of complex steps and selecting appropriate parameters, which can be challenging for researchers without bioinformatics expertise.
- Cloud ATAC is an open-source, cloud-based framework designed to simplify ATAC-seq analysis, leveraging Google Cloud for computational resources and Jupyter Notebook for interactive learning, with publicly available source codes and learning materials.