Publications by authors named "Dajin Yang"

Introduction: Enterococci are considered opportunistic pathogens. However, they can serve as a reservoir of antibacterial resistance (ABR) traits and transfer these to humans through the food chain.

Methods: Antibiotic susceptibility testing and multilocus sequence typing were used to characterize the ABR and population structure of 488 enterococcal isolates recovered along the food chain from four provincial-level administrative divisions (PLADs) in China.

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  • - The study assesses pathogenic bacteria prevalence in raw livestock meat (pork, beef, mutton) in China for 2021, with a focus on antimicrobial resistance (AMR) to inform public health and food safety practices.
  • - Out of 2,515 meat samples, contamination rates were highest in pork for certain pathogens, with specific prevalence noted in chilled and frozen meat compared to fresh.
  • - The study found high overall resistance rates in bacteria isolated from meat, with ampicillin and tetracycline showing the most significant resistance among the tested antimicrobial agents.
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  • This study investigated antibiotic resistance in bacterial isolates from seafood and freshwater sources in China, showing that a significant majority (95.31%) of isolates were resistant to at least one antibiotic.
  • The research revealed a high prevalence of beta-lactam and tetracycline resistance, with 1.56% of isolates classified as multi-drug resistant (MDR).
  • The study also found notable genetic diversity among the isolates, with 34 different genetic types, highlighting the importance of monitoring these bacteria to protect food safety and public health.
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The possible contamination routes, environmental adaptation, and genetic basis of Cronobacter spp. in infant and follow-up formula production factories and retailed products in mainland China have been determined by laboratory studies and whole-genome comparative analysis in a 7-year nationwide continuous surveillance spanning from 2012 to 2018. The 2-year continuous multicenter surveillance of the production process (conducted in 2013 and 2014) revealed that the source of Cronobacter spp.

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Rare Earth Elements (REEs) have been implicated in potential health effects. However, the health risk of REE exposure among tea drinkers in China remains poorly understood. This study aimed to characterize the concentration of REEs in different tea categories and evaluate the associated health risks for tea consumers in China.

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Methods for regioselective -trideuteromethylation of tautomeric polyaza heterocycles are highly sought-after. Disclosed herein is an -trideuterated methylation reaction of imidazoles and pyrazoles with high regioselectivity and deuterium purity using easily available CFSOCD as the -CD source. This method enables the easy synthesis of important deuterium-labeled azoles, including dimetridazole-, ipronidazole-, hydroxy dimetridazole-, and ronidazole-.

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Prevalent in marine, estuarine and coastal environments, Vibrio parahaemolyticus is one of the major foodborne pathogens which can cause acute gastroenteritis through consumption of contaminated food. This study encompassed antimicrobial resistance, molecular characteristics and phylogenetic relationships of 163 V. parahaemolyticus isolated from aquatic foods across 15 provinces in China.

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  • Paralytic shellfish toxins (PSTs) pose a significant health threat in coastal China, but comprehensive studies and risk assessments are still lacking.
  • A study collected 641 shellfish samples from March to November 2020, finding PSTs in 241 samples (37.60% detection rate), with mussels and ark shells having notably higher toxicity levels.
  • Seasonal variations showed higher PST toxicity in spring, particularly in Hebei Province, raising dietary risk concerns for consumers, especially regarding mussels.
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Refined and deodorized camellia oil has been reported to contain a high amount of 3-monochloropropane-1,2-diol esters (3-MCPDE) due to the high-temperature deodorization step. To reduce 3-MCPDE in camellia oil, the physical refining process of camellia oil was simulated on a laboratory scale. Response surface methodology (RSM) was designed to modify and optimize the refining process with five processing parameters (water degumming dosage, degumming temperature, activated clay dosage, deodorization temperature and deodorization time).

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Microbial contamination in raw milk and dairy products can detrimentally affect product quality and human health. In this study, the aerobic plate count, aerobic abundance, thermophilic aerobic abundance, and alkaline phosphatase activity were determined in 435 raw milk, 451 pasteurized milk, and 617 sterilized milk samples collected from 13 Chinese provinces (or municipalities). Approximately 9.

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Rare earth elements (REEs) are widely found in foods. A high intake of REEs may have associations with adverse effects on human health. This study aimed to investigate the concentrations of REEs in foods in China and to assess the risk of dietary REEs exposure in the Chinese population.

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Antibiotics, especially fluoroquinolones, have been exhaustively used in animal husbandry. However, very limited information on the occurrence and exposure assessment of fluoroquinolone residues in chicken and pork in China is available to date. Thus, a total of 1754 chicken samples and 1712 pork samples were collected from 25 provinces in China and tested by ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for residual determination of six common fluoroquinolones.

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For a long time, () was thought to be a commensal strain in human and animal digestive tracts. However, over the past three decades, some unique clones rapidly acquired multiple antimicrobial resistance (AMR), which led these clones to survive hospital environments and become a hospital-adapted clonal complex (CC) 17. Since the adaptation of these clones to changes in habitat, vancomycin-resistant CC17 has emerged as the leading cause of hospital-acquired infections worldwide.

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Objective: To investigate the microbial contamination in dried fruit products in China.

Methods: In 2019, 2917 samples of dried fruit products on the market were collected, and examined for aerobic bacterial count, coliforms, molds, yeasts, Salmonella and Listeria monocytogenes according to the method specified in GB 4789.

Results: A total of 34.

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The contents of perchlorate and chlorate were determined in a total of 278 samples of infant formulas marketed in China. The associated health risk via infant and young child formulas consumption for 0-36 month old children in China was also assessed. The contents of perchlorate and chlorate were measured by a validated method with LC-MS and the limit of detection (LOD) was 1.

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National foodborne pathogen surveillance is a system that collects data regarding food contamination by pathogenic bacteria, viruses, parasites, and other harmful microbial factors. The surveillance data are used to understand the potential microbial risks in different categories of food and to provide science-based data for risk assessment and development of reference standards in the form of maximum limits. This review introduces stepwise expansion of the foodborne pathogen surveillance in China, relevant policies, function and duties of different organizations and institutions, surveillance plans, and quality control.

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The presence of 3-monochloropropane-1,2-diol (3-MCPD) esters and 2-MCPD esters in infant formulas have raised a number of food safety concerns. Here, a dietary exposure assessment was conducted for 3-and 2-MCPD esters in infant formulas available for consumption in Chinese infant and toddlers aged 0-3 years old. This work presents the occurrence data for 3-and 2-MCPD ester in 874 infant formulas purchased in China between 2015 and 2017.

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A method for the preparation and certification of the reference material of tenuazonic acid (TeA) and tentoxin (TEN) in wheat flour was developed. This method provided methodological references to develop of standard material for analyzing alternaria toxins in grains. The wheat flour reference materials were based on wheat grains which were naturally contaminated with alternaria toxins.

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Staphylococcus aureus is a worldwide leading cause of numerous diseases ranging from food-poisoning to lethal infections. Methicillin-resistant S. aureus (MRSA) has been found capable of acquiring resistance to most antimicrobials.

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Peanuts in China are heavily contaminated with aflatoxin, which pose a threaten to human health. To compare the dietary exposure risk of aflatoxins (AFT) in peanuts and peanut oil in different areas of China, the spatial distribution of AFT contamination levels in peanuts and peanut oil from different areas was analyzed. The dietary exposure was calculated by simple distributed risk assessment method before characterizing the health risk using both the margin of exposure (MOE) approach proposed by the European Food Safety Authority (EFSA) and the quantitative liver cancer risk approach proposed by the Joint Food and Agricultural Organization/World Health Organization (FAO/WHO) Expert Committee on Food Additives (JECFA).

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Objective: To investigate the occurrence data for fatty acid esters of chloropropanol and glycidyl in edible vegetable oils purchased in China.

Methods: The 1309 samples of edible vegetable oil were collected and the data of chloropropanol and glycidyl were detected by the gas chromatography-mass spectrometry from 2015 to 2017.

Results: The detection rate of 3-monochloropropanediol esters in vegetable oils was 81.

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The aim of this study was to develop a comparative risk assessment method to prioritise the public health risks posed by chemical hazards in food. Through a literature review, and in light of expert opinions, a bottom-up, semi-quantitative scoring method was applied to screen the ranking metrics and assign a score. In addition, a metrics system and a ranking model were constructed.

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Article Synopsis
  • Edible oils and oil-containing foods are primary sources of 3-monochloropropane-1,2-diol (3-MCPD) esters, prompting analysis of 3,847 food samples from various regions in China between 2015-2017.
  • The study found the mean levels of 3-MCPD esters in edible oils, fried foods, and bakery items to be relatively low, with daily intake estimates generally below the tolerable limits set by the European Food Safety Authority.
  • While most of the Chinese population faces low health risks from 3-MCPD esters, individuals with high oil consumption may exceed safety thresholds, requiring further attention to their dietary habits.
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Deoxynivalenol (DON) is one of the most commonly found mycotoxins across the world, and it mainly contaminates staple food crops. This study aims to evaluate the dietary exposure of DON and to provide a geographical profile of DON exposure in China. The concentrations of DON and its acetylated derivatives in 15,004 cereal samples (10,192 wheat flour, 1750 maize meal, 892 oat flakes, and 2170 polished rice) were collected from 30 provinces, autonomous regions, or municipalities across China during 2010-2017, through a national food safety risk surveillance system.

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Salmonellosis is a challenge to public health globally, and many infections have been principally linked to the consumption of contaminated eggs. The objective of this study is to estimate the prevalence of Salmonella in commercial eggs and susceptibilities of isolates to a panel of 14 antimicrobial agents which were determined according to Clinical and Laboratory Standards Institute (CSLI) procedures. A total of 33,288 eggs (5548 pooled samples of six eggs) were collected across China in 2016 and the prevalence of Salmonella was 0.

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