Background: To explore the kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19.
Methods: This observational study enrolled 20 patients with COVID-19, who were hospitalized between January 20-April 6, 2020, in the two COVID-19 designated hospitals of Zhoushan, Zhejiang and Rushan, Shandong, China, The laboratory findings, imaging, serum response to viral infection, and viral RNA level in the throat and stool samples were assessed from onset to recovery phase in patients with COVID-19.
Results: SARS-COV-2 RNA was positive as early as day four.