Publications by authors named "Daisy V Zavala"
Article Synopsis
- The study investigates loneliness and social isolation during the COVID-19 pandemic, focusing on age differences and how they may vary by region and time within the first year of the crisis.
- Data from four studies with a total of 1,307 participants were analyzed using common variables and statistical methods to explore how social interactions influenced feelings of loneliness, particularly considering age as a factor.
- Results showed that social interactions were generally linked to lower loneliness levels, with consistent patterns observed across different pandemic phases; importantly, no significant age-related differences were found in these associations.
DNA methylation-derived epigenetic clocks offer the opportunity to examine aspects of age acceleration (ie, the difference between an individual's biological age and chronological age), which vary among individuals and may better account for age-related changes in cognitive function than chronological age. Leveraging existing ambulatory cognitive assessments in daily life from a genetically diverse sample of 142 adults in midlife, we examined associations between 5 measures of epigenetic age acceleration and performance on tasks of processing speed and working memory. Covarying for chronological age, we used multilevel models to examine associations of epigenetic age acceleration (Horvath 1, Horvath 2, Hannum, PhenoAge, and GrimAge clocks) with both average level and variability of cognitive performance.
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