A case of advanced gastric cancer showing HER2 positivity after chemotherapy.

A 63-year-old man had advanced poorly differentiated gastric adenocarcinoma with para-aortic lymph node metastases. No HER2 expression was observed in four endoscopic biopsies from the primary tumor. Tumors shrunk after S-1 with cisplatin treatment, and he underwent simple gastrectomy due to stenosis.

Anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease, successfully treated with modified FOLFOX6: a case report.

Background: Anal canal cancer occasionally accompanies extramammary Paget disease. Although most of them are squamous cell carcinoma, anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease has never been reported.

Case Presentation: Here, we report a 76-year-old man presented with pruritus in the perianal area.

Successful Long-term Management with a Single Administration of Tri-weekly Nab-paclitaxel in a Patient with Advanced Gastric Cancer with Peritoneal Dissemination.

Nanoparticle albumin-bound (nab)-paclitaxel has shown promising activity in advanced gastric cancer treatment. We herein report a case of advanced gastric cancer involving long-term management with a single administration of nab-paclitaxel. A 71-year-old man diagnosed with advanced gastric cancer with malignant ascites was treated with nab-paclitaxel as a second-line chemotherapy.

Fan-in/out polymer optical waveguide for a multicore fiber fabricated using the mosquito method.

A fan-in/out polymer optical waveguide with 25-μm cores and 40-μm interchannel pitch is fabricated for a multimode multicore fiber using a microdispenser. We design a fan-in/out structure to which the Mosquito method is applicable since the Mosquito method is capable of drawing a circular graded-index core three-dimensionally. Then, we experimentally fabricate a 10-cm long fan-in/out polymer waveguide with seven cores, which is expected to connect a multicore fiber and a fiber ribbon.

Accurate interchannel pitch control in graded-index circular-core polymer parallel optical waveguide using the Mosquito method.

We successfully fabricate polymer optical waveguides with graded-index (GI) circular cores whose diameter and interchannel pitch are accurately controlled using the Mosquito method: GI-core waveguides with 250-, 125- and 62.5-μm pitches are successfully obtained. The Mosquito method utilizing a microdispenser is a very simple technique for fabricating GI-circular-core polymer optical waveguides.