Publications by authors named "Daisuke Matsuki"
Article Synopsis
- Tumor metastasis to lymph nodes remains a significant cause of cancer-related deaths, prompting research into better treatment methods.
- This study explores a novel cancer therapy using external laser light to release doxorubicin (DOX) from thermosensitive liposomes (TSLs), aided by gold nanorods (GNRs) injected into a mouse model.
- The combined treatment using chemotherapy and laser-induced hyperthermia showed promising results, significantly inhibiting tumor growth and leading to tumor necrosis, indicating potential for developing a non-surgical treatment option for breast cancer metastasis.
Intravenous chemotherapy has poor access to metastatic lymph nodes (LNs) and is limited by short-lived drug concentrations. Here, we describe the administration of chemotherapy via the lymphatic network as a new concept for the prevention and treatment of metastatic LNs. A metastatic LN can be treated by the injection of drugs into an upstream LN, either the sentinel LN (SLN) or another upstream LN.
View Article and Find Full Text PDF