Publications by authors named "Daisuke Ikechi"
Background: Severe metformin intoxication can lead to lactic acidosis and vasoplegic shock, for which the optimal management strategy remains uncertain, especially in cases of severe circulatory collapse.
Case Presentation: A 45-year-old diabetic woman on metformin therapy presented with impaired consciousness and seizures. She had experienced a cardiac arrest and undergone extracorporeal cardiopulmonary resuscitation.
Article Synopsis
- A study was conducted to explore the effectiveness of panoramic ultrasound in assessing the rectus femoris muscle by comparing its cross-sectional area to its volume measured via CT scans.
- The research involved 20 hospitalized patients, with assessments done at the beginning and end of the week, and found significant correlations between changes in muscle area and volume.
- The findings suggest that panoramic ultrasound is a reliable method for measuring muscle mass in critically ill patients, as it correlates well with CT results.
Background: The nitrogen balance estimates a protein net difference. However, since it has a number of limitations, it is important to consider the trajectory of the nitrogen balance in the clinical course of critically ill patients.
Objectives: We herein exploratively classified the nitrogen balance trajectory using a machine learning method.
Article Synopsis
- - Vasopressin is an alternative treatment for severe septic shock, but loading doses aren’t typically used due to safety concerns; this study explores its potential benefits and safety through a planned loading approach.
- - In this study, 92 patients receiving noradrenaline for septic shock were monitored, with those showing a significant increase in mean arterial pressure (MAP) after a vasopressin loading dose classified as responders; results showed differences in hormonal levels and cardiac function between responders and non-responders.
- - The study found that responders had notable changes in the catecholamine index after six hours, indicating better overall response to vasopressin, with a high AUROC value suggesting effective prediction of treatment response, although
Adequate protein delivery is recommended in the acute phase of critical illness with kidney dysfunction. However, the influence of the protein and nitrogen loads has not yet been clarified. Patients admitted to the intensive care unit were included.
View Article and Find Full Text PDFObjectives: Post-intensive care syndrome (PICS) is a recognised sequela after critical care. The development of an index that predicts PICS mental disorders will be of significance for the selection of subsequent interventions. The purpose of this study was to find factors associated with PICS mental disorders.
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- * It highlights new guidance developed by a working group on managing heat stroke amidst the COVID-19 pandemic, incorporating updated research from multiple sources.
- * The second edition of this guidance focuses on critical aspects such as indoor ventilation, mask safety, and the isolation of older adults, aiming to improve prevention and treatment strategies for heat stroke during the ongoing pandemic.
Purpose: We hypothesized that coagulopathy independently contributes to muscle injury focusing to titin fragmentation, and investigated their correlations.
Material And Methods: We conducted a post-hoc analysis of an observational study, in which we evaluated muscle injury with the biomarker titin. Coagulopathy was assessed on the first day using the Japanese diagnostic criteria of acute-phase disseminated intravascular coagulopathy (JAAM-DIC).
Diarrhea is one of the most common complications associated with enteral nutrition in hospitalized patients. Oligomeric enteral nutrition has been considered to reduce the incidence of diarrhea. We herein introduced and examined the effects of a specific oligomeric enteral nutrition with the low-molecular-weight whey peptides, Peptino in critically ill patients with refractory diarrhea or at high risk of mesenteric ischemia.
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