Publications by authors named "Daiki Yoshiura"
Background: The global use of angiotensin receptor neprilysin inhibitor (ARNI) in clinical practice, especially in patients with heart failure and below-normal ejection fraction (HFbnEF), has not been thoroughly evaluated. We aimed to investigate the characteristics, outcomes, and adverse events in patients treated with ARNI for HF with reduced (HFrEF), below-normal (HFbnEF), and supranormal left ventricular EF (HFsnEF).
Methods: This observational study analyzed data from the electronic healthcare records (EHR) of patients with HF treated with ARNI between 2015 and 2022 in North and South America, Europe, the Middle East, Africa, and Asia-Pacific.
Article Synopsis
- A 76-year-old woman with a background of repeated pulmonary edema experienced a sudden increase in shortness of breath and cardiogenic shock.
- The medical team discovered that eclipsed mitral regurgitation was the underlying cause of her condition.
- They diagnosed and evaluated her treatment using hand-grip stress echocardiography and successfully managed her situation through a transcatheter edge-to-edge mitral valve repair.
Late gadolinium enhancement (LGE) in cardiovascular magnetic resonance imaging (CMR) prevents left ventricular reverse remodeling (LVRR), resulting in a poor prognosis. However, the prognosis of patients who have LGE and achieve LVRR and patients who do not have LGE and do not achieve LVRR remains unknown. This study aimed to answer this question by sorting patients with heart failure based on the presence of LGE and LVRR and comparing their prognoses.
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- This study examines the effects of percutaneous left atrial appendage closure (LAAC) on left atrial volume index (LAVI) and its implications for patients with atrial fibrillation (AF).* -
- Researchers analyzed 225 patients and found no overall significant change in LAVI six months after LAAC, but some patients did experience increases, particularly those with smaller baseline LAVI and higher tricuspid regurgitation pressure.* -
- An increase in LAVI was linked to a higher risk of heart failure hospitalization, especially in patients with a baseline LAVI greater than 55 ml/m.*
(1) : In patients with heart failure (HF) and impaired nutritional status or decreased muscle mass, sodium-glucose cotransporter-2 inhibitors (SGLT2is) may worsen these conditions and result in poor prognosis, especially worsening of frailty. We aimed to investigate the relationship between SGLT2is and clinical outcomes, including frailty-related events, in patients with HF and malnutrition, frailty, sarcopenia, or cachexia. (2) : In this retrospective observational cohort study, a global federated health research network provided data on patients with HF and malnutrition, frailty, sarcopenia, or cachexia from January 2016 to December 2021.
View Article and Find Full Text PDFPostnatal development of hippocampal function has been reported in many mammalian species, including humans. To obtain synaptic evidence, we analyzed developmental changes in plasticity after an inhibitory avoidance task in rats. Learning performance was low in infants (postnatal 2 weeks) but clearly improved from the juvenile period (3-4 weeks) to adulthood (8 weeks).
View Article and Find Full Text PDFBackground: Renal impairment is a common phenomenon that portends a poor prognosis of heart failure (HF). The renal arterial resistance index (RRI) can be useful for defining renal function and predicting outcomes in patients with HF. This study aimed to investigate the determining factors of the RRI in HF patients with preserved ejection fraction (HFpEF) and with reduced EF (HFrEF).
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