Publications by Daiki Kuboyama

Publications by authors named "Daiki Kuboyama"

ACS Meas Sci Au

April 2023

* The device demonstrated high efficiency, with over 96% recovery of tumor cells and more than 99% removal of leukocytes in our experiments.
* In clinical applications, we successfully extracted DNA from microfiltered CTCs and detected key mutations, which can aid in assessing targeted lung cancer treatments.

Daiki Kuboyama's recent research focuses on improving the isolation of circulating tumor cells (CTCs) from whole blood, addressing challenges related to cellular stress and purity in liquid biopsies.
The study introduces a novel blood microfiltration device that utilizes pressure sensing to effectively separate CTCs from leukocytes, which are typically abundant in blood samples.
Findings demonstrate an impressive average recovery rate of over 96% for tumor cells while achieving over 99% depletion of leukocytes, highlighting the device's potential for enhancing the accuracy and efficiency of noninvasive cancer diagnostics.