Clinical significance of ribosomal protein S15 expression in patients with colorectal cancer liver metastases.

Background: Liver metastasis is the most frequently observed distant metastasis of colorectal cancer, and the residual liver recurrence rate after hepatic resection is still high. To explore the mechanism of liver metastasis to discover potential new treatments, we assessed the relationship between the expression of differentially expressed genes (DEGs) and prognosis in patients with colorectal cancer liver metastasis (CRLM).

Methods: The gene expression dataset was extracted from The Cancer Genome Atlas and the Gene Expression Omnibus.

Analysis of Short-Term and Long-Term Outcomes of Living Donor Liver Transplantation for Patients with a High Model for End-Stage Liver Disease Score.

Background: The Model of End-Stage Liver Disease (MELD) scoring system can predict short-term survival among patients awaiting liver transplantation and is used to allocate organs prioritizing liver transplantation. Patients with high MELD scores have been reported to have worse early graft dysfunction and survival. However, recent studies have shown that patients with high MELD scores had satisfactory graft survival, although they showed more postoperative complications.

[A Case of Radical Resection of an Initially Unresectable Intrahepatic Cholangiocarcinoma with Lymph Node Metastasis Invading the Proper Hepatic Artery-Made Possible by the Effective Impact of Preoperative Chemotherapy].

A 57-year-old man was diagnosed with an intrahepatic cholangiocarcinoma(ICC)located at segment 4, attached to the hilar bile ducts, with metastasis of the lymph nodes bordering the right hepatic artery. The ICC was unresectable, and chemotherapy with GCS was administered for 7 months. Although the primary tumor site did not change after the chemotherapy, the lymph nodes shrunk slightly and we decided to perform conversion surgery(CS).