Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice.

Aim: To investigate the effect of probiotic supplementation during the development of an experimental model of colitis associated colon cancer (CAC).

Methods: C57BL/6 mice received an intraperitoneal injection of azoxymethane (10 mg/kg), followed by three cycles of sodium dextran sulphate diluted in water (5% w/v). Probiotic group received daily a mixture of , and .