Thiazole, Isatin and Phthalimide Derivatives Tested against Cancer Models: A Literature Review of the Last Six Years.

Background: Cancer is a disease characterized by the abnormal multiplication of cells and is the second leading cause of death in the world. The search for new effective and safe anticancer compounds is ongoing due to factors such as low selectivity, high toxicity, and multidrug resistance. Thus, heterocyclic compounds derived from isatin, thiazole and phthalimide that have achieved promising anticancer activity have been tested in vivo and in clinical trials.