Concordance rate between oligoclonal bands and the Kappa index in patients with suspected multiple sclerosis (MS).

Background:  Oligoclonal bands (OCBs) and Kappa free light chains (FLCs) in the cerebrospinal fluid (CSF) are sensitive markers of intrathecal immunoglobulin (Ig)G synthesis in patients with multiple sclerosis.

Objective:  To evaluate the concordance rate between OCBCs and the Kappa index (KI) in patients with suspected multiple sclerosis (MS).

Methods:  Patients with suspected MS were referred to a specialized CSF laboratory as part of their diagnostic investigation.