Sample Preparation Approaches for Determination of Quinolones in Aqueous Matrixes: Systematic Review.

Quinolones and fluoroquinolones are among the most used antibiotics worldwide. Antibiotic resistance genes can be acquired by human pathogens from ambient microorganisms, which can lead to a treatment failure for bacterial infections. Furthermore, determining the levels of quinolones and fluoroquinolones in aqueous matrixes is crucial for safeguarding both human health and the environment.

Magnetic solid phase extraction based on restricted access molecularly imprinted polymer with dually coated for enantioselective determination of tramadol in human plasma by capillary electrophoresis with ultraviolet detection.

A restricted-access magnetic molecularly imprinted polymer with dually coated of hydrophilic monomer and bovine serum albumin was synthesized, properly characterized by different techniques, and used as adsorbent in Magnetic Solid Phase Extraction (MSPE). Furthermore, a simple and efficient method employing capillary electrophoresis with ultraviolet detection was developed and validated for the enantioselective determination of tramadol (TRM) in human plasma. The optimized conditions were 25 mM phosphate background electrolyte at pH 9.