Xanthene-based near-infrared chromophores for high-contrast fluorescence and photoacoustic imaging of dipeptidyl peptidase 4.

Near-infrared (NIR) chromophores with analyte tunable emission and absorption properties are highly desirable for developing activatable fluorescence and photoacoustic (PA) probes for bioimaging and disease diagnosis. Here we engineer a class of new chromophores by extending the π-conjugation system of a xanthene scaffold at position 7 with different electron withdrawing groups. It is demonstrated that these chromophores exhibit pH-dependent transition from a spirocyclic "closed" form to a xanthene "open" form with remarkable changes in spectral properties.

Changing trends, clinicopathological characteristics, surgical treatment patterns, and prognosis of schistosomiasis-associated versus non-schistosomiasis-associated colorectal cancer: a large retrospective cohort study of 31 153 cases in Shanghai, China (2001-2021).

Background: With the elimination of schistosomiasis in China, its role in the pathogenesis of colorectal cancer (CRC) has decreased. However, the trends, clinicopathological features, surgical treatment patterns, and prognosis of schistosomiasis-associated CRC (SACRC) versus non-schistosomiasis-associated CRC (NSACRC) in China remain unclear.

Materials And Methods: The percentage trend of SACRC in CRC patients in China was analyzed using data retrieved from the Pathology Registry of Changhai Hospital (2001-2021).

Contributions and achievements on schistosomiasis control and elimination in China by NIPD-CTDR.

Being a zoonotic parasitic disease, schistosomiasis was widely spread in 12 provinces of Southern China in the 1950s, severly harming human health and hindering economic development. The National Institute of Parasitic Diseases at the Chinese Center for Diseases Control and Prevention, and Chinese Center for Tropical Diseases Research (NIPD-CTDR), as the only professional institution focussing on parasitic diseases at the national level, has played an important role in schistosomiasis control in the country. In this article, we look back at the changes of schistosomiasis endemicity and the contribution of NIPD-CTDR to the national schistosomiasis control programme.

Assessment of knowledge, attitude and practices and the analysis of risk factors regarding schistosomiasis among fishermen and boatmen in the Dongting Lake Basin, the People's Republic of China.

Background: Fishermen and boatmen are a population at-risk for contracting schistosomiasis due to their high frequency of water contact in endemic areas of schistosomiasis in the People's Republic of China (P. R. China).

Imported Schistosomiasis, China, 2010-2018.

China has made remarkable progress in reducing schistosomiasis caused by Schistosoma japonicum over the past 7 decades but now faces a severe threat from imported schistosomiasis. Results from national surveillance during 2010-2018 indicate integrating active surveillance into current surveillance models for imported cases is urgently needed to achieve schistosomiasis elimination in China.

Change patterns of oncomelanid snail burden in areas within the Yangtze River drainage after the three gorges dam operated.

Background: An "integrated control" strategy has been implemented within seven provinces at highest risk for schistosomiasis along Yangtze River in Peoples' Republic of China (P. R. China) since 2004.

[Analysis of schistosomiasis cases report in National Notifiable Disease Report System in China, 2015-2017].

Objective: To understand the reporting situation of schistosomiasis cases in National Notifiable Disease Report System (NNDRS) in China from 2015 to 2017, and to seek current deficiencies on case reporting as well as to analyze the epidemiological characteristics of schistosomiasis cases.

Methods: The data of schistosomiasis cases in China from 2015 to 2017 were collected from NNDRS, and the reporting situation and epidemiological characteristics of schistosomiasis cases were analyzed.

Results: From 2015 to 2017, totally 59 981 schistosomiasis cases were reported in China, among which, 1 460 cases were deleted, and 58 521 were censored cases.

The epidemiological status of schistosomiasis in P. R. China after the World Bank Loan Project, 2002-2017.

World Bank Loan Project (WBLP) for schistosomiasis control conducted from 1992 to 2001, resulted in significant reduction of schistosomiasis morbidity and mortality in People's Republic of China (P.R. China), with implementation of morbidity control.

[Endemic status of schistosomiasis in People's Republic of China in 2017].

This report presents the endemic status of schistosomiasis in the People's Republic of China at national level in 2017, and analyzes the data collected from the national schistosomiasis prevention and control system and 457 national schistosomiasis surveillance sites. Among the 12 provinces (municipality and autonomous region) being endemic of schistosomiasis japonica in P. R.

[Progress of research on association between schistosomiasis and single nucleotide polymorphisms].

Single nucleotide polymorphisms (SNP) has been regarded as a new genetic marker due to its rich dynamics and relatively stable heredity. SNP can express the relationship between genes and diseases to seek disease-linked genes particularly. A number of domestic and international studies have demonstrated that the formation of schistosomiasis egg granuloma is closely linked to HLA-Ⅱ related antigen.

Di-isopropyl ether assisted crystallization of organic-inorganic perovskites for efficient and reproducible perovskite solar cells.

Organic-inorganic perovskite solar cells have emerged as a promising photovoltaic technology because of their advantages such as low cost, high efficiency, and solution processability. The performance of perovskite solar cells is highly dependent on the crystallinity and morphology of the perovskite films. Herein, we report a simple, one-step anti-solvent deposition process using di-isopropyl ether as a dripping solvent to obtain extremely uniform and highly crystalline CHNHPbI perovskite films.

Tailorable PC BM Isomers: Using the Most Prevalent Electron Acceptor to Obtain High-Performance Polymer Solar Cells.

Despite being widely used as electron acceptor in polymer solar cells, commercially available PC BM (phenyl-C -butyric acid methyl ester) usually has a "random" composition of mixed regioisomers or stereoisomers. Here PC BM has been isolated into three typical isomers, α-, β - and β -PC BM, to establish the isomer-dependent photovoltaic performance on changing the ternary composition of α-, β - and β -PC BM. Mixing the isomers in a ratio of α/β /β =8:1:1 resulted in the best power conversion efficiency (PCE) of 7.

[ snail distribution in working areas of Yangtze River hydrologic agencies located in middle and lower reaches of Yangtze River in 2016].

Objective: To understand the snail distribution in the working areas of Yangtze River hydrologic agencies located in the middle and lower reaches of the Yangtze River in 2016, so as to provide the evidence for assessing the risk of schistosome infection of hydrological workers and establishing the control strategies.

Methods: The suspicious environments with snails in the above working areas were selected as study areas, and the snail situation was surveyed by the system sampling method combined with the environmental sampling method. The survey data were collected and analyzed statistically.

Efficient Perovskite Solar Cells Depending on TiO2 Nanorod Arrays.

Perovskite solar cells (PSCs) with TiO2 materials have attracted much attention due to their high photovoltaic performance. Aligned TiO2 nanorods have long been used for potential application in highly efficient perovskite solar cells, but the previously reported efficiencies of perovskite solar cells based on TiO2 nanorod arrays were underrated. Here we show a solvothermal method based on a modified ketone-HCl system with the addition of organic acids suitable for modulation of the TiO2 nanorod array films to fabricate highly efficient perovskite solar cells.