Hydrogen gas holds immense promise as a clean fuel source, yet its widespread adoption faces significant challenges in storage and transportation due to its gaseous and highly flammable nature. An increasingly attractive approach to overcoming these limitations involves reacting aluminum (Al) blocks with water to produce hydrogen, providing an alternative distribution mechanism in which Al blocks can be used as "hydrogen storage" for on-demand production at any location. However, current methods suffer poor hydrogen production rates and yields, primarily influenced by the limited contact area between Al and the catalyst, such as Ga-based room-temperature liquid metal.
View Article and Find Full Text PDFTEMPO-CNF film modified by two-dimension transition metal MXene has certain antibacterial properties. However, the problem of long-lasting stability greatly restricts the feasibility of long-term use of the composite film. Here, we introduced polyaniline (PANI) as a modifying molecule, which was electrostatically adsorbed on the surface of the MXene nanosheets to prevent its self-stacking and delay its oxidation.
View Article and Find Full Text PDFIn situ bone regeneration and vertical bone augmentation have been huge problems in clinical practice, always imposing a significant economic burden and causing patient suffering. Herein, MgZnYNd magnesium alloy rod implantation in mouse femur resulted in substantial subperiosteal new bone formation, with osteoimmunomodulation playing a pivotal role. Abundant macrophages were attracted to the subperiosteal new bone region and proved to be the most important regulation cells for bone regeneration.
View Article and Find Full Text PDFCalcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic epithelial tumor characterized by the presence of amyloid material within the tumor that can undergo calcification. CEOT affects individuals across a broad age range, typically between 20 and 60 years, with an average onset age of 40 years. However, it is extremely rare in children and adolescents.
View Article and Find Full Text PDFThe aim of this study was to investigate the effects and potential mechanisms of 8-week transcranial direct-current stimulation (tDCS) combined with resistance training (RT) on pull-up performance in male college students. Twenty-five male college students were randomly assigned to either RT combined with anodal tDCS stimulation (RT + tDCS) or RT alone (RT). Participants of both groups engaged in lat pull-down training programs for 8 weeks, with the RT + tDCS group receiving 20 min tDCS before each RT session.
View Article and Find Full Text PDFMost land plants form symbioses with microbes to acquire nutrients but also must restrict infection by pathogens. Here, we show that a single pair of lysin-motif-containing receptor-like kinases, MpaLYR and MpaCERK1, mediates both immunity and symbiosis in the liverwort Marchantia paleacea. MpaLYR has a higher affinity for long-chain (CO7) versus short-chain chitin oligomers (CO4).
View Article and Find Full Text PDFPalladium (Pd) catalysts are promising for electrochemical reduction of CO to CO but often can be deactivated by poisoning owing to the strong affinity of *CO on Pd sites. Theoretical investigations reveal that different configurations of *CO endow specific adsorption energies, thereby dictating the final performances. Here, a regulatory strategy toward *CO absorption configurations is proposed to alleviate CO poisoning by simultaneously incorporating Cu and Zn atoms into ultrathin Pd nanosheets (NSs).
View Article and Find Full Text PDFPolysaccharide hydrocolloids have garnered increasing attention from consumers, experts, and food processing industries due to their advantages of abundant resources, favorable thickening properties, emulsification stability, biocompatibility, biodegradability, and high acceptance as food additives. This review focuses on the application of polysaccharide hydrocolloids and their beneficial roles in meat products by focusing on several commonly used polysaccharides (i.e.
View Article and Find Full Text PDFBackground: Constipated patients may exhibit anxious behaviors, but the relationship between the two remains unclear. This population-based study aims to investigate the relationships of anxiety status and anxiety duration with constipation among U.S.
View Article and Find Full Text PDFObjective: An increasing number of antiseizure medications (ASMs) are approved for monotherapy for focal epilepsy, but direct comparisons of the lifetime cost-effectiveness of all existing treatment strategies are lacking. This study aims to compare the cost-effectiveness of new ASMs and traditional ASMs as first-line monotherapy for newly diagnosed focal epilepsy.
Method: We used a Markov model to evaluate the lifetime cost-effectiveness of 10 ASMs in the treatment of focal epilepsy, with lacosamide (LCM) as a control, from the perspective of society in the United States.
Background: Sarcopenia, an aseptic chronic inflammatory disease, is a complex and debilitating disease characterized by the progressive degeneration of skeletal muscle. PANoptosis, a novel proinflammatory programmed cell death pathway, has been linked to various diseases. However, the precise role of PANoptosis-related features in sarcopenia remains uncertain.
View Article and Find Full Text PDFBackground: The C-repeat binding factor (CBF)/dehydration-responsive element binding (DREB1) belongs to a subfamily of the AP2/ERF (APETALA2/ethylene-responsive factor) superfamily, which can regulate many physiological and biochemical processes in plants, such as plant growth and development, hormone signal transduction and response to abiotic stress. Although the CBF/DREB1 family has been identified in many plants, studies of the CBF/DREB1 family in alfalfa are insufficient.
Results: In this study, 25 MsCBF genes were identified in the genome of alfalfa ("Zhongmu No.
Purpose: We aimed to conduct a retrospective analysis to assess the efficacy and safety of finerenone in patients with membranous nephropathy (MN).
Methods: This study conducted a retrospective analysis of patients with MN who were treated with finerenone for follow-up period ranging from 3 to 6 months. The study compared the estimated glomerular filtration rate (eGFR), urine total protein-to-creatinine ratio (PCR), urine albumin-to-creatinine ratio (ACR), serum creatinine concentration (SCr), blood pressure and serum potassium (K+) during the follow-up period.
Curcumin has a great effect on alleviating oxidative stress, but its poor stability and low biocompatibility limit its application in therapeutic field. In order to overcome these limitations of curcumin, in this study, curcumin was grafted to lignin by esterification, and then prepared into nanoparticles. The results showed that the photothermal stability of curcumin was effectively improved.
View Article and Find Full Text PDFColor-tunable white organic light-emitting diodes (CT-WOLEDs) have attracted widespread attention given their large color variation to meet the different daily scenarios from the perspective of circadian rhythm. However, most reported CT-WOLEDs, especially the tri-color devices, exhibit poor performances and sophisticated structures. Here, a simple structure tri-color CT-WOLED is demonstrated that simultaneously exhibits high efficiency, ultralong operation lifetime, and wide color-tunable range for dynamic sunlight emulation.
View Article and Find Full Text PDFMacrophages play a crucial role in the immune response during allograft rejection in organ transplantation. Therefore, our study aimed to explore the genomic features of macrophages in mouse heart transplants and use single-cell RNA sequencing to investigate Galectin-9 (Gal-9, Lgals9), a lectin that can mediate the activation and differentiation of immune cells through ligand-receptor interactions, and the effects of its regulation in transplantation. We discovered a new subset of macrophages called "Myoz2+ macrophages", which specifically expressed genes related to myocardial contraction.
View Article and Find Full Text PDFBackground: Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer with alarmingly high morbidity. The cancer-associated fibroblasts (CAFs) play a pivotal role in tumor development, while their specific mechanisms in OSCC remains largely unclear. Our object is to explore a CAFs-related biomarker in OSCC.
View Article and Find Full Text PDFBackground: The foodborne pathogens, e.g., Salmonella typhimurium (S.
View Article and Find Full Text PDFThe application of neonicotinoid insecticides (NEOs) increases the potential exposure risks and has an impact on the aroma quality of tomato fruits. Here, 3D cornflower-like MoS (MoS-CF) was fabricated to directly activate peroxymonosulfate (PMS) for fast removal of three typical NEOs. The 3D MoS-CF catalyst achieved over 96.
View Article and Find Full Text PDFNuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy contributes to maintain intracellular iron balance by regulating ferritin degradation, which is essential for redox homeostasis. CXC-motif chemokine receptor 3 (CXCR3) is involved in the regulation of oxidative stress and autophagy. However, its role in modulating intestinal oxidative damage through ferritinophagy and the gut microbiota remains unclear.
View Article and Find Full Text PDFSpirulina platensis (SP) provides humans with proteins and natural pigments. The effects of micro/nanoplastics (MNPs) on SP are of great interest. We focused on the effects of high concentrations (100-300 mg/L) of polystyrene MNPs on SP for 50 days.
View Article and Find Full Text PDFBackground: Lipoid pneumonia (LP) is a rare disease caused by the accumulation of lipids and lipid-laden macrophages in the alveoli inducing damage. LP is difficult to differentiate from other similar diseases without pathological evidence, such as upper respiratory tract infection (URTI), pneumonia, cryptogenic organizing pneumonia (COP), pulmonary alveolar proteinosis (PAP), lung mucinous adenocarcinoma and pulmonary edema. Given the high misdiagnosis rate and limited statistical clinical and treatment data, there is an urgent need for novel indicators of LP.
View Article and Find Full Text PDFEndocrinol Diabetes Metab
January 2025
Objective: This study investigates the relationship between the albumin-to-creatinine ratio and diabetic retinopathy (DR) in US adults using NHANES data from 2009 to 2016. This study assesses the predictive efficacy of the urinary serum albumin-to-creatinine ratio (UACR/SACR Ratio) against traditional biomarkers such as the serum albumin-to-creatinine ratio (SACR) and urinary albumin-to-creatinine ratio (UACR) for evaluating DR risk. Additionally, the study explores the potential of these biomarkers, both individually and in combination with HbA1c, for early detection and risk stratification of DR.
View Article and Find Full Text PDFBMC Public Health
January 2025
Background: eHealth literacy (eHL) is positively associated with health-related behaviors and outcomes. Previous eHL studies primarily collected data from online users and seldom focused on the general population in low- and middle-income countries (LMIC). Additionally, knowledge about factors that affect eHL is limited.
View Article and Find Full Text PDFPurpose: Optimal treatment strategies for patients with hepatocellular carcinoma (HCC) with oligoprogression after first-line systemic therapy (FLST) remain undefined. We aimed to determine if maintaining [i.e.
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