How do lesions affect limb lengthening in children with Ollier's disease?

Purpose: Ollier's disease (multiple enchondromatosis) can cause severe lower limb length discrepancy and deformity in children. Osteotomy and limb lengthening with external fixation can correct the lower extremity deformity. There may be lesions in the osteotomy part (OP), and the internal fixation part of the external fixation(FP).

Efficacy of the cross-union protocol in the treatment of congenital tibial pseudarthrosis: a comparative study.

Background: Congenital Pseudarthrosis of the Tibia (CPT) is a rare pediatric condition presenting substantial challenges for orthopedic surgeons. Aiming to achieve bone union, with subsequent complications such as refractures being common. The aim of the present study is to evaluate the results of our intentional cross-union protocol and to compare these outcomes with those obtained from our previously used techniques.

Conservative treatment for traumatic atlantoaxial joint infra-anterior dislocation complicating odontoid fracture in young children: A case series.

Purpose: The purpose of this study is to retrospectively analyze children treated conservatively in our hospital to explore the clinical characteristics of children with traumatic atlantoaxial joint infra-anterior dislocation complicating odontoid fracture and the therapeutic effects of treatment.

Methods: Patients with atlantoaxial joint infra-anterior dislocation complicating odontoid fracture received conservative treatment, which comprised three steps: cervical traction (2 weeks), plaster fixation (2 months), and brace fixation (3 months).

Results: We treated three patients (boy:girl = 0:3, mean age = 2.

A model for predicting AKI after cardiopulmonary bypass surgery in Chinese patients with normal preoperative renal function.

Objective: To develop and validate a predictive model for acute kidney injury (AKI) after cardiopulmonary bypass (CPB) surgery in Chinese patients with normal preoperative renal function.

Method: From January 1, 2015, to September 1, 2022, a total of 1003 patients were included in the analysis as a development cohort. We used the ratio of 7:3 to divide the patients into a training group (n = 703) and a testing group (n = 300).

Early synaptic dysfunction of striatal parvalbumin interneurons in a mouse model of Parkinson's disease.

In Parkinson's disease (PD), the loss of dopaminergic signaling remodels striatal circuits, causing abnormal network activity. The timing and impact on various striatal cell types during this reorganization are unclear. Here we demonstrate that dopamine depletion rapidly reduces parvalbumin (PV) expression.

Origin and factors for overgrowth in pediatric fractures of the femoral shaft after flexible intramedullary nail fixation.

Background: Leg length discrepancy is a common complication following flexible intramedullary nail (FIN) fixation for femoral shaft fractures in adolescents. This retrospective study was designed to evaluate the possible cause of femoral overlengthening in children with femoral shaft fracture.

Methods: We retrospectively included 138 patients diagnosed with femoral shaft fractures between June 2012 and December 2022 and reported the clinical/radiological outcomes after at least half a year of surgery.

Use of Artificial Intelligence in Cobb Angle Measurement for Scoliosis: Retrospective Reliability and Accuracy Study of a Mobile App.

Background: Scoliosis is a spinal deformity in which one or more spinal segments bend to the side or show vertebral rotation. Some artificial intelligence (AI) apps have already been developed for measuring the Cobb angle in patients with scoliosis. These apps still require doctors to perform certain measurements, which can lead to interobserver variability.

Evaluation of the efficacy of posterior hemivertebrectomy combined with two or more segments fusion.

Background: Although early hemivertebra (HV) resection and short fusion (within 4 segments) have been successful in treating congenital HV, there is limited research comparing the outcomes of the shortest-segment fusion (2 segments) versus 3 or 4 segments, particularly in young children. To evaluate the efficacy of posterior hemivertebrectomy combined with two or more segments fusion in children under the age of 10 years with a solitary simple lower thoracic or lumbar HV (T8-L5).

Methods: This retrospective study included patients under the age of 10 with lower thoracic or lumbar solitary simple HV who underwent hemivertebra resection (HVR) and transpedicular short fusion and were divided into HV ± 1 group (2 segment fusion) and HV ± 2 group (3 or 4-segment fusion).

Study on Basic Pavement Performance of High-Elasticity Asphalt Concrete.

In order to improve the basic pavement performance of high-elastic asphalt concrete filled in the expansion longitudinal joints of seamless bridges, rubber particles and polyester fibers were added to optimize the mix proportion of elastic asphalt concrete, and the optimal asphalt-aggregate ratio was determined. The influence of rubber particles and polyester fibers on the basic pavement performance of high-elastic asphalt concrete was studied. The results show that when the dosage of polyester fiber is not more than 0.

Carbon/copper oxide electrode materials with high atomic utilization constructed by in-situ induced growth strategy of nano metal-organic frameworks.

Carbon/metal composites derived from metal-organic frameworks (MOFs) have attracted widespread attention due to their excellent electronic conductivity, adjustable porosity, and outstanding stability. However, traditional synthesis methods are limited by the dense stereo geometry and large crystal grain size of MOFs, resulting in many metals active sites are buried in the carbon matrix. While the common strategy involves incorporating additional dispersed media into material, this leads to a decrease in practical metal content.

Processing Language Partly Shares Neural Genetic Basis with Processing Tools and Body Parts.

Language is an evolutionarily salient faculty for humans that relies on a distributed brain network spanning across frontal, temporal, parietal, and subcortical regions. To understand whether the complex language network shares common or distinct genetic mechanisms, we examined the relationships between the genetic effects underlying the brain responses to language and a set of object domains that have been suggested to coevolve with language: tools, faces (indicating social), and body parts (indicating social and gesturing). Analyzing the twin datasets released by the Human Connectome Project that had functional magnetic resonance imaging data from human twin subjects (monozygotic and dizygotic) undergoing language and working memory tasks contrasting multiple object domains (198 females and 144 males for the language task; 192 females and 142 males for the working memory task), we identified a set of cortical regions in the frontal and temporal cortices and subcortical regions whose activity to language was significantly genetically influenced.

Abnormal coagulation after hepatectomy in patients with normal preoperative coagulation function.

Background: To explore the risk factors for postoperative abnormal coagulation (PAC) and establish a predictive model for patients with normal preoperative coagulation function who underwent hepatectomy.

Materials And Methods: A total of 661 patients with normal preoperative coagulation function who underwent hepatectomy between January 2015 and December 2021 at the First Affiliated Hospital of Sun Yat-sen University were divided into two groups: the postoperative abnormal coagulation group (PAC group, n = 362) and the normal coagulation group (non-PAC group, n = 299). Univariate and multivariate logistic analyses were used to identify the risk factors for PAC.

Association Between Triglyceride Glucose Index with Cognitive Impairment and Dementia in Adult Population: A Meta-Analysis.

The current understanding of the correlation between insulin resistance (IR) and cognitive dysfunction is limited. Therefore, the objective of this systematic review and meta-analysis was to assess the association between the triglyceride glucose (TyG) index, a recently suggested indicator of IR, and cognitive impairment and dementia in the adult population. Observational studies pertinent to our research were identified through comprehensive searches of the PubMed, Embase, and Web of Science databases.

Ulnar osteotomy between the proximal 1/3 and 1/5 provides a stable radiocapitellar joint in chronic Monteggia fracture.

Background: The precise location of unlar osteotomy remains a subject of ongoing controversy in chronic Monteggia fracture (CMF). The purpose of this study was to analyze the influence of different levels of ulnar osteotomy on redislocation in CMF.

Methods: We retrospectively reviewed 18 children following our previous series.

Category representation in primary visual cortex after visual perceptual learning.

Unlabelled: The visual perceptual learning (VPL) leads to long-term enhancement of visual task performance. The subjects are often trained to link different visual stimuli to several options, such as the widely used two-alternative forced choice (2AFC) task, which involves an implicit categorical decision. The enhancement of performance has been related to the specific changes of neural activities, but few studies investigate the effects of categorical responding on the changes of neural activities.

γ And β Band Oscillation in Working Memory Given Sequential or Concurrent Multiple Items: A Spiking Network Model.

Working memory (WM) can maintain sequential and concurrent information, and the load enhances the γ band oscillation during the delay period. To provide a unified account for these phenomena in working memory, we investigated a continuous network model consisting of pyramidal cells, high-threshold fast-spiking interneurons (FS), and low-threshold nonfast-spiking interneurons (nFS) for working memory of sequential and concurrent directional cues. Our model exhibits the γ (30-100 Hz) and β (10-30 Hz) band oscillation during the retention of both concurrent cues and sequential cues.