Publications by authors named "Dahong He"
Article Synopsis
- Rhein has the potential to slow down chronic nephropathy progression, but its exact mechanisms are not well understood yet.
- This study used various methods, including metabolomics and western blotting, to examine how rhein affects cell and animal models of kidney fibrosis.
- Results indicate that rhein influences certain metabolic pathways and signaling proteins, suggesting its therapeutic effects on chronic nephropathy could be linked to these biological processes.
The traditional Chinese medicine (Miq.) Seem., also known as , has the effect of "tonifying Qi and calming the mind, strengthening the essence and tonifying the kidneys, and dispelling wind and invigorating blood circulation".
View Article and Find Full Text PDFBrain organoids are new tool for drug screening of neurological diseases.
Neural Regen Res
September 2023
Article Synopsis
- The paper discusses the creation of a phenotypic analysis system using brain organoids to improve high-throughput drug screening, especially for traditional Chinese medicine.
- It emphasizes the benefits of brain organoids over traditional induced neurons or cells in studying diseases and conducting drug tests.
- The review covers key aspects such as the stability of brain organoids, methods for their induction, and innovative screening strategies tailored to their unique characteristics.
Evidence from experimental and clinical studies implicates immuno-inflammatory responses as playing an important role in epilepsy-induced brain injury. Captopril, an angiotensin-converting enzyme inhibitor (ACEi), has previously been shown to suppress immuno-inflammatory responses in a variety of neurological diseases. However, the therapeutic potential of captopril on epilepsy remains unclear.
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