Can Histological Grade and Mitotic Index Replace Ki67 to Determine Luminal Breast Cancer Subtypes?

Introduction: Breast cancer can be classified into subtypes based on immunohistochemical markers, with Ki67 expression levels being used to divide luminal BC tumors in luminal A and B subtypes; however, Ki67 is not routinely determined due to a lack of standardization. Objective: To evaluate histological grade and Eliminate: the mitotic index to determine if they can be used as an alternative method to Ki67 staining for luminal subtype definition. Methods: We evaluated estrogen receptor positive breast cancer tissue samples.

Clinicopathologic subtypes and compromise of lymph nodes in patients with breast cancer.

Unlabelled: Breast cancer (BC) is currently a heterogeneous disease with variations in clinical behaviour. Classification according to subtypes has allowed progress in the individualisation of treatment. The objective of this study is to evaluate the risk of axillary node compromise in patients with BC, according to clinicopathologic subtypes.

Plethysmographic lung volumes in normal Chilean children and adolescents.

Introduction: Plethysmographic measurement is the most reliable method for evaluating lung volumes in children. Current published normative data are based on studies in primarily Caucasian children.

Objectives: To establish Chilean normal values with new reference equations and to compare these results with previously published data.

[Empyema and pleural effusion in children].

Introduction: Pleural empyema (PE) is a serious complication of community-acquired pneumonia (CAP).

Objectives: To describe the clinical profile of hospitalized patients with PE in the pediatric ward of the Catholic University Hospital between 2000-2005.

Patients And Methods: Retrospectively, all pediatric admission due to CAP and pleural effusion (86 children) were identified.