Publications by authors named "Daher Cezar Chade"
Introduction: Non-metastatic, castration-resistant prostate cancer (nmCRPC) is an important clinical stage of prostate cancer, prior to morbidity and mortality from clinical metastases. In particular, the introduction of novel androgen-receptor signaling inhibitors (ARSi) has changed the therapeutic landscape in nmCRPC. Given recent developments in this field, we update our recommendations for the management of nmCRPC.
View Article and Find Full Text PDFConsensus on Screening, Diagnosis, and Staging Tools for Prostate Cancer in Developing Countries: A Report From the First Prostate Cancer Consensus Conference for Developing Countries (PCCCDC).
JCO Glob Oncol
April 2021
Purpose: To generate and present the survey results on critical issues relevant to screening, diagnosis, and staging tools for prostate cancer (PCa) focused on developing countries.
Methods: A total of 36 of 300 questions concern the main areas of interest of this paper: (1) screening, (2) diagnosis, and (3) staging for various risk levels of PCa in developing countries. A panel of 99 international multidisciplinary cancer experts voted on these questions to create recommendations for screening, diagnosing, and staging tools for PCa in areas of limited resources discussed in this manuscript.
Article Synopsis
- The study aimed to identify clinical and pathological factors affecting complications, survival, and cancer recurrence in patients undergoing multivisceral en bloc resection for colorectal cancer.
- Between January 2009 and February 2014, 105 patients were analyzed, revealing significant statistics like a 37.1% morbidity rate, a 1.9% 30-day mortality rate, and varying rates of recurrence after surgery.
- Key findings indicated that factors such as positive surgical margins and lymph node involvement contributed to poorer oncological outcomes and lower overall survival rates, with lymph node involvement being the most influential factor.
Context: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma.
Case Report: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient.