Zhonghua Yi Xue Yi Chuan Xue Za Zhi
December 2003
Objective: To examine the effect of SH2A gene in cell signal transduction and its subcellular localization.
Methods: RT-PCR method was used to amplify the coding sequence of SH2A gene. Eukaryotic recombined expression vector pcDNA 3.
Background & Objective: There may be a close relationship among the vascular endothelial growth factor-C (VEGF-C) expression, peritumour lymphatic vessels, and lymph node metastasis. The purpose of this study was to compare the relationship among VEGF-C mRNA expression, density of lymphatic and blood vessels, and lymphatic metastasis in oral squamous carcinoma.
Methods: VEGF-C mRNA was determined by RT-PCR.