Expression level of CEBPA gene in acute lymphoblastic leukemia individuals.

Currently, acute lymphoblastic leukemia (ALL) has an overall survival of nearly 80% when it occurs in children, however cure rates among adults are far reduced. Leukemogenesis can be driven up by a slight change in the expression or function of certain transcription factors. CCAAT Enhancer Binding Protein Alpha (CEBPA) is a transcription factor with role in cell cycle regulation, granulocytic differentiation and more.

Expression levels of the runt-related transcription factor 1 and 3 genes in the development of acute myeloid leukemia.

The aim of the present study was to evaluate the mRNA expression level of the runt-related transcription factor 1 () and runt-related transcription factor 3 () genes in patients with acute myeloid leukemia (AML). The etiology of AML is not yet fully known, but certain genetic factors may contribute to its manifestation. The and genes have been demonstrated to serve a role in the transcription process.