Role of NT-proBNP in detection of myocardial damage in childhood leukemia survivors treated with and without anthracyclines.

Background: Exposure to anthracyclines (ANT) during childhood represents a high risk for development of late cardiotoxicity. Cardiotoxicity is usually detected only when clinical symptoms or progressive cardiac dysfunction have already occurred. Early detection of cardiotoxicity may lead to better therapeutic outcome.

Heart transplant in a childhood leukemia survivor: a case report.

Objectives: Children with acute leukemia often receive therapy that is potentially cardiotoxic. Development of irreversible cardiac impairment requiring heart transplant may appear many years after anticancer therapy. Other possible causes are discussed.

[Severe heart failure in consequence of late anthracycline-induced cardiotoxicity--case report].

Background: Anthracyclines are known cardiotoxic agents. Anthracycline therapy increases the risk of long-term cardiac adverse effects in oncology patients.

Case Report: We report the case of a young male patient with severe congestive heart failure.