Precise Yet Uncertain: Broadening Understandings of Uncertainty and Policy in the BPA Controversy.

Bisphenol A (BPA) is one of the most studied and most controversial chemicals used by the food packaging industry, because of its endocrine disruptive properties. Part of the controversy is due to the uncertainty that surrounds the effects of BPA on the endocrine system. Uncertainty includes data gaps, methodological hurdles, incompatibilities between toxicology and endocrinology-based approaches, and so on.

Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster.

Cytokinesis, the final step of cell division, conventionally proceeds to cell separation by abscission, or complete cytokinesis, but may in certain tissues be incomplete, yielding daughter cells that are interconnected in syncytia by stable intercellular bridges. The mechanisms that determine complete versus incomplete cytokinesis are not known. Here we report a novel in vivo role of the Drosophila CD2AP/CIN85 ortholog Cindr in both complete and incomplete cytokinesis.